Cavaillon Jean-Marc
Unité Cytokines & Inflammation, Institut Pasteur, 28 Rue Dr. Roux, 75014, Paris, France.
Crit Care. 2014 Aug 14;18(4):486. doi: 10.1186/s13054-014-0486-0.
Altered immune status of blood leukocytes is a general phenomenon observed in adult patients with sepsis or septic shock. This is also the case in children with septic shock for both T helper 1 and T helper 2 lymphocytes, as demonstrated by their reduced ex vivo cytokine production upon activation by phytohemagglutinin.
血液白细胞免疫状态改变是成年脓毒症或脓毒性休克患者中观察到的普遍现象。脓毒性休克患儿的辅助性T细胞1和辅助性T细胞2淋巴细胞也存在这种情况,这可通过它们在被植物血凝素激活后体外细胞因子产生减少得到证明。