Yuan Jianming, Guan Yuening, Zhao Zhifeng, Shen Jiankang, Tan Dan, Zhao Fang, Ge Lei, Xie Rongli, Li Tingting
Department of General Surgery, Ruijin Hospital Luwan Branch, Shanghai Jiaotong University School of Medicine, 149 Chongqing South Road, Huangpu District, Shanghai, China.
Department of Gastrointestinal Surgery, Xijing Hospital, Fourth Military Medical University, No.127, West Changle Road, Xi'an, Shaanxi Province, China.
Int Health. 2025 Sep 3;17(5):678-684. doi: 10.1093/inthealth/ihaf012.
The objective was to investigate the implications of enteral nutrition for elderly patients with common-type coronavirus disease 2019 (COVID-19).
Data were retrospectively extracted from medical records. Enteral nutritional supplementation was recommended for patients with a nutritional risk score >3. The preferred method was oral administration, and preparations included Ensure and TPF-T. Continuous variables were compared using analysis of two-tailed Student's t-tests or one-way analysis of variance for normally distributed data and the rank sum test for non-normally distributed data. Categorical variables were compared using the χ2 test or Fisher's exact test. Values of p <0.05 were considered to be statistically significant.
The mortality rate in the whole cohort was 9.54%. A total of 474 patients tested negative and were discharged; among them, 173 patients received enteral nutrition while 301 patients did not. There were significant correlations between mortality and age, serum albumin concentration, prognostic nutritional index, underlying severe disease status and diet condition. In patients with a poor diet, early use of enteral nutrition is associated with faster conversion to a negative polymerase chain reaction test.
The prognosis of elderly patients with common-type COVID-19 was related to their nutritional status. Enteral nutritional supplementation is the preferred method of nutrition because it is the simplest and most widely accepted method for patients. For patients with poor diet conditions, enteral nutritional intervention should be performed early.
目的是探讨肠内营养对老年普通型新型冠状病毒肺炎（COVID-19）患者的影响。
从病历中回顾性提取数据。营养风险评分>3的患者建议进行肠内营养补充。首选方法是口服，制剂包括安素和TPF-T。连续变量采用双尾t检验或方差分析（用于正态分布数据）以及秩和检验（用于非正态分布数据）进行比较。分类变量采用χ2检验或Fisher精确检验进行比较。p<0.05的值被认为具有统计学意义。
整个队列的死亡率为9.54%。共有474例患者检测阴性并出院；其中，173例患者接受了肠内营养，301例患者未接受。死亡率与年龄、血清白蛋白浓度、预后营养指数、潜在重症疾病状态和饮食状况之间存在显著相关性。在饮食不佳的患者中，早期使用肠内营养与更快转为聚合酶链反应检测阴性相关。
老年普通型COVID-19患者的预后与其营养状况有关。肠内营养补充是首选的营养方法，因为它对患者来说是最简单且最广泛接受的方法。对于饮食状况不佳的患者，应尽早进行肠内营养干预。
