Yu Siqi, Wang Huan, Sledziewski Jill E, Madhira Venkata N, Takahashi Cyrus G, Leon Michelle K, Dudkina Yulia B, Budnikova Yulia H, Vicic David A
Department of Chemistry, Lehigh University, 6 E. Packer Ave., Bethlehem, PA 18015, USA.
Department of Chemistry, University of Hawaii, 2545 McCarthy Mall, Honolulu, HI 96822, USA.
Molecules. 2014 Sep 2;19(9):13603-13. doi: 10.3390/molecules190913603.
New well-defined, paramagnetic nickel complexes have been prepared and characterized by X-ray crystallography. The complexes were found to be active for the cross-coupling of alkyl electrophiles (especially ethyl 2-bromobutyrate) with alkyl Grignard reagents. The ligand architecture in these new complexes could potentially be rendered chiral, opening up future possibilities for performing asymmetric cross-coupling reactions.
新型结构明确的顺磁性镍配合物已被制备出来，并通过X射线晶体学进行了表征。发现这些配合物对于烷基亲电试剂（特别是2-溴丁酸乙酯）与烷基格氏试剂的交叉偶联反应具有活性。这些新型配合物中的配体结构有可能被转化为手性结构，为进行不对称交叉偶联反应开辟了未来的可能性。
