Turel Iztok
Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, SI-1000 Ljubljana, Slovenia.
Molecules. 2015 Apr 30;20(5):7951-6. doi: 10.3390/molecules20057951.
In 1913 Alfred Werner received the Nobel Prize in Chemistry for his work that was of great importance for the development of coordination chemistry. In the years that followed numerous complexes consisting of metal ions and organic ligands were isolated, thus building a strong connection between inorganic and organic chemistry. Coordination compounds have many interesting properties which find diverse applications in numerous aspects of human life. Fourteeen contributions were received for this Special Issue covering very different aspects of metal complexes and their practical applications. The highest number of manuscripts deals with the biological activity of complexes which might potentially be used in the clinical practice. Authors have tested their cytotoxicity, antibacterial activity and enzyme inhibition. Their optical properties were studied in view of their potential use in photodynamic therapy. Moreover, optical properties could also be used for bioanalysis. It is also known that metal complexes are useful catalysts and a few such examples are also described herein. Many other interesting properties and facts about the isolated and described complexes are also reported (radioactivity, design of metal-organic frameworks, etc.).
1913年，阿尔弗雷德·维尔纳因其对配位化学发展具有重要意义的工作而获得诺贝尔化学奖。在随后的几年里，许多由金属离子和有机配体组成的配合物被分离出来，从而在无机化学和有机化学之间建立了紧密的联系。配位化合物具有许多有趣的性质，在人类生活的诸多方面有着广泛的应用。本期特刊共收到14篇稿件，涵盖了金属配合物及其实际应用的非常不同的方面。稿件数量最多的是关于配合物的生物活性，这些配合物可能会被用于临床实践。作者们测试了它们的细胞毒性、抗菌活性和酶抑制作用。鉴于它们在光动力疗法中的潜在用途，对其光学性质进行了研究。此外，光学性质也可用于生物分析。还已知金属配合物是有用的催化剂，本文也描述了一些这样的例子。关于分离和描述的配合物的许多其他有趣的性质和事实也有报道（放射性、金属有机框架的设计等）。
