Kawamura S
Shika Kiso Igakkai Zasshi. 1989 Feb;31(1):72-82. doi: 10.2330/joralbiosci1965.31.72.
The purpose of this study was to examine the effects of chewing a hard and soft diet on acquisition of conditioned avoidance response in mice and rats. 76 C57BL mice and 38 Wistar rats were divided into 2 groups respectively 20 days after birth. One group was fed a solid diet and another was fed a powder diet containing the same components as the solid one (Nihon Crea Company, CE-2). Using the avoidance conditioning system of Gunma University, conditioned avoidance experiments started at the age of 8 weeks and the rate of avoidance (number of avoidance/number of trials) was measured. The mean percentage of avoidance rates in the solid diet group were significantly higher than those of powder diet group at level of 1% in mice and 5% in rats. These results suggest that mastication of a hard diet in younger animal may facilitate their brain function more than that of a soft diet.
本研究的目的是检验小鼠和大鼠咀嚼硬质和软质食物对条件性回避反应习得的影响。76只C57BL小鼠和38只Wistar大鼠在出生后20天分别分为两组。一组喂食固体食物，另一组喂食含有与固体食物相同成分的粉末状食物（日本克雷亚公司，CE-2）。使用群马大学的回避条件化系统，在8周龄时开始进行条件性回避实验，并测量回避率（回避次数/试验次数）。在小鼠中，固体食物组的平均回避率百分比在1%水平时显著高于粉末状食物组；在大鼠中，在5%水平时也是如此。这些结果表明，幼年动物咀嚼硬质食物可能比咀嚼软质食物更能促进其脑功能。
