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达托霉素治疗粪肠球菌所致人工关节感染：高剂量及延长疗程的安全性与疗效

Daptomycin in the treatment of prosthetic joint infection by Enterococcus faecalis: safety and efficacy of high-dose and prolonged therapy.

作者信息

Yuste José Ramón, Quesada Milena, Díaz-Rada Pablo, Del Pozo José Luis

机构信息

Division of Infectious Diseases, Clinica Universidad de Navarra, Pamplona, Spain; Department of Internal Medicine, Clinica Universidad de Navarra, Pamplona, Spain.

Division of Infectious Diseases, Clinica Universidad de Navarra, Pamplona, Spain.

出版信息

Int J Infect Dis. 2014 Oct;27:65-6. doi: 10.1016/j.ijid.2014.05.034. Epub 2014 Sep 2.

DOI:10.1016/j.ijid.2014.05.034
PMID:25192907
Abstract

Enterococci are implicated in less than 2.3% of prosthetic joint infections. These infections can be difficult to treat and therapeutic failures are not uncommon. In these situations, daptomycin is a safe and effective alternative. We present a clinical case with a successful response to the prolonged use of high-dose daptomycin.

摘要

肠球菌在不到2.3%的人工关节感染中起作用。这些感染可能难以治疗，治疗失败并不罕见。在这些情况下，达托霉素是一种安全有效的替代药物。我们报告一例长期使用高剂量达托霉素获得成功治疗的临床病例。

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