日本一株大肠杆菌ST648分离株中首次发现新德里金属β-内酰胺酶-7。
A first case of New Delhi metallo-β-lactamase-7 in an Escherichia coli ST648 isolate in Japan.
作者信息
Mizuno Yasutaka, Yamaguchi Tetsuo, Matsumoto Tetsuya
机构信息
Department of Infectious Diseases, Tokyo Medical University, Shinjuku, Tokyo, Japan.
Department of Microbiology, Tokyo Medical University, Shinjuku, Tokyo, Japan.
出版信息
J Infect Chemother. 2014 Dec;20(12):814-6. doi: 10.1016/j.jiac.2014.08.009. Epub 2014 Sep 3.
We report a first identification case of an Escherichia coli ST648 isolate producing a variant New Delhi metallo-β-lactamase (NDM) -7 in Japan, which was recovered from a patient hospitalized in India. Although the first isolate, NDM-1, was identified in Japan in 2010, NDM-producing bacteria have only been isolated from seven patients to date, and no other variant of NDM producing organism has been reported yet. The emergence of NDM variants in Enterobacteriaceae is of great concern, and the use of rigorous screening tests and preventive measures against infection is imperative.
我们报告了在日本首次鉴定出一株产新型德里金属β-内酰胺酶（NDM）-7变体的大肠杆菌ST648分离株，该菌株是从一名在印度住院的患者身上分离得到的。尽管2010年在日本首次鉴定出NDM-1分离株，但迄今为止，仅从7名患者身上分离出产NDM的细菌，且尚未报告其他产NDM生物体的变体。肠杆菌科中NDM变体的出现备受关注，因此必须采用严格的筛查试验和感染预防措施。
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