Saelzer E, Alarcón T, Miquel I, Muñoz P, Parraguez A
Rev Med Chil. 1989 Dec;117(12):1387-92.
Plasma levels of d-xylose one hr after a standard 5 g oral dose were measured in 82 children suspected of having celiac disease. Duodenal mucosa was obtained by intestinal biopsy in all. Among patients with normal mucosa, 95% had xylose levels above 20 mg/dl; 100% of patients with a flat mucosa had levels under 20 mg/dl. Results were independent of patients age. We conclude that this is a reliable test to screen patients suspected of having celiac disease, prior to intestinal biopsy.
对82名疑似患有乳糜泻的儿童，在口服5克标准剂量的d-木糖后1小时测量其血浆水平。所有患儿均通过肠道活检获取十二指肠黏膜。在黏膜正常的患者中，95%的d-木糖水平高于20毫克/分升；黏膜扁平的患者中100%的水平低于20毫克/分升。结果与患者年龄无关。我们得出结论，在进行肠道活检之前，这是一种筛查疑似乳糜泻患者的可靠检测方法。
