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[应激机制与药理学应激源阻断]

[Stress mechanisms and pharmacological stressor blockade].

作者信息

Vargas Fernández L

出版信息

Rev Med Chil. 1989 Aug;117(8):922-9.

PMID:2519455
Abstract

A biomedicine approach to stress mechanisms is developed. Stress, stages are illustrated as symbolic gear transmissions. Stressor transit through the organism leads to final stage characterized by behavioral changes. Anticholinergic and antiadrenergic agents may be used to investigate stressor pathway. This kind of research suggest that the stressor goes into the hypothalamic region through the cholinergic system and goes out of it through and adrenergic pathway. The third ventricle occupying the hypothalamic region is the location where orders for stress response can be traced.

摘要

一种针对应激机制的生物医学方法被开发出来。应激阶段被描述为象征性的齿轮传动。应激源在机体中的传导导致以行为变化为特征的最终阶段。抗胆碱能和抗肾上腺素能药物可用于研究应激源途径。这类研究表明,应激源通过胆碱能系统进入下丘脑区域,并通过肾上腺素能途径离开该区域。占据下丘脑区域的第三脑室是可以追踪应激反应指令的位置。

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