Tzelepis Elias, Kampolis Christos F, Vlachadami Ioanna, Moschovi Maria, Alamani Maria, Kaltsas Gregory
Department of Pathophysiology, 'Laiko' Hospital, University of Athens Medical School, Athens, Greece.
Department of Pediatrics, University of Athens Medical School, Athens, Greece.
Clin Respir J. 2016 Mar;10(2):250-4. doi: 10.1111/crj.12206. Epub 2014 Oct 2.
Sweet's syndrome or acute febrile neutrophilic dermatosis is characterized by fever, leukocytosis and tender erythematous plaques, which show infiltration by mature neutrophils on histological examination. Pulmonary involvement is rare in Sweet's syndrome.
We describe the case of a 17-year-old man with a myelodysplastic syndrome following therapy for Hodgkin's lymphoma who developed Sweet's syndrome and cryptogenic organizing pneumonia. In addition, we conducted a review of the related English literature.
Literature review yielded six similar reports of biopsy-proven cryptogenic organizing pneumonia associated with Sweet's syndrome. We present the clinical and laboratory characteristics, as well as the response to treatment, of all cases of cryptogenic organizing pneumonia reported in patients with Sweet's syndrome.
Cryptogenic organizing pneumonia is a rare manifestation of Sweet's syndrome, which may be complicated by respiratory failure. Prompt treatment with corticosteroids usually leads to clinical and radiographic improvement.
斯威特综合征或急性发热性嗜中性皮病的特征为发热、白细胞增多以及压痛性红斑斑块，组织学检查显示有成熟嗜中性粒细胞浸润。斯威特综合征肺部受累罕见。
我们描述了一名17岁男性病例，该患者在接受霍奇金淋巴瘤治疗后发生骨髓增生异常综合征，并出现了斯威特综合征和隐源性机化性肺炎。此外，我们对相关英文文献进行了综述。
文献综述得出6例经活检证实的与斯威特综合征相关的隐源性机化性肺炎的类似报告。我们展示了斯威特综合征患者中报告的所有隐源性机化性肺炎病例的临床和实验室特征以及对治疗的反应。
隐源性机化性肺炎是斯威特综合征的一种罕见表现，可能并发呼吸衰竭。及时使用皮质类固醇治疗通常会导致临床和影像学改善。
