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处方药滥用的类型学:一种基于潜在类别分析方法对差异和危害的研究

A typology of prescription drug misuse: a latent class approach to differences and harms.

作者信息

Kelly Brian C, Rendina H Jonathon, Vuolo Mike, Wells Brooke E, Parsons Jeffrey T

机构信息

Department of Sociology, Purdue University, West Lafayette, USA; Research Center, Center for HIV Educational Studies and Training, New York, USA.

出版信息

Drug Alcohol Rev. 2015 Mar;34(2):211-20. doi: 10.1111/dar.12192. Epub 2014 Sep 6.

Abstract

INTRODUCTION AND AIMS

Prescription drug misuse is a considerable problem among young adults, and the identification of types of misuse among this population remains important for prevention and intervention efforts. We use latent class analysis to identify possible distinct latent groups of prescription drug misusers across multiple prescription drug types (pain killers, sedatives and stimulants).

DESIGN AND METHODS

Our data are comprised of a sample of 404 young adults recruited from nightlife scenes via time-space sampling. Through the specification of a zero-inflated Poisson latent class analysis, we evaluate differences in class membership by various demographic factors as well as assess the relationship between class membership and health outcomes, including indications of dependence, problems associated with substance use and mental health.

RESULTS

Our assessment of fit indices led to a four-class solution (dabblers, primary stimulant users, primary downers users and extensive regulars). No demographic differences existed between latent classes. The extensive regular class report the greatest number of symptoms related to dependence, greatest number of problems related to misuse and the greatest mental health problems. The dabblers report the fewest problems and symptoms, while the other two classes experiences problems and symptoms in between the classes on the extremes.

DISCUSSION AND CONCLUSIONS

Prevention efforts should take into account that young adults who misuse prescription drug have different profiles of misuse, and there may be a need for varied interventions to target these different types of misuse.

摘要

引言与目的

处方药滥用在年轻人中是一个相当严重的问题,识别该人群中的滥用类型对于预防和干预工作仍然很重要。我们使用潜在类别分析来识别多种处方药类型(止痛药、镇静剂和兴奋剂)的可能不同的潜在处方药滥用群体。

设计与方法

我们的数据由通过时空抽样从夜生活场所招募的404名年轻人组成。通过零膨胀泊松潜在类别分析的设定,我们评估不同人口统计学因素在类别归属上的差异,并评估类别归属与健康结果之间的关系,包括依赖迹象、与物质使用相关的问题和心理健康。

结果

我们对拟合指数的评估得出了一个四类解决方案(涉猎者、主要兴奋剂使用者、主要镇静剂使用者和广泛规律使用者)。潜在类别之间不存在人口统计学差异。广泛规律使用者报告的与依赖相关的症状数量最多,与滥用相关的问题数量最多,心理健康问题也最多。涉猎者报告的问题和症状最少,而其他两类在极端情况之间经历问题和症状。

讨论与结论

预防工作应考虑到滥用处方药的年轻人有不同的滥用模式,可能需要针对这些不同类型的滥用采取不同的干预措施。

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