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外伤性前房积血是否需要局部使用皮质类固醇激素?

Is topical corticosteroid necessary in traumatic hyphema?

作者信息

Türkoğlu E B, Celik T, Celik E, Ozkan N, Bursalı O, Coşkun S B, Alagoz G

机构信息

Akdeniz University, Department of Ophthalmology, 07100 Antalya, Turkey.

Bolu Gerede State Hospital Department of Ophthalmology, Seviller St., 14900 Gerede-Bolu, Turkey.

出版信息

J Fr Ophtalmol. 2014 Oct;37(8):613-7. doi: 10.1016/j.jfo.2014.04.007. Epub 2014 Sep 6.

Abstract

PURPOSE

To compare the outcomes in the management of traumatic hyphema treated with topical corticosteroid plus supportive therapy versus only supportive therapy.

PATIENTS AND METHODS

In this retrospective study, 206 patients were divided into two groups; group I, 98 eyes were treated with topical corticosteroid 12 × 1 and supportive therapy including bed rest, keeping the head elevated (45 degrees), and hydration. In group II, 108 eyes were treated with only supportive therapy. Hyphema size, initial and final visual acuities and intraocular pressure, time to hyphema clearance, and incidence of rebleeding were evaluated.

RESULTS

The time needed for hyphema resorption in the two groups were 60.25 ± 33.9 and 62.3 ± 28.9 hours respectively (P=0.62). There was no significant difference in rebleeding rate between the topical corticosteroid group (4.01%) and non-steroid group (6.48%) (P=0.67). The initial and final visual acuities were similar in the two groups (P=0.86). In Groups I and II, the average intraocular pressures were 19.7 ± 8.01 and 14.2 ± 10.2 mmHg respectively. The difference between the two groups was statistically significant (P=0.04).

CONCLUSION

Patients who were treated with topical corticosteroids were no less likely to experience a rebleed or a poor visual outcome than those treated with supportive therapy alone. Supportive therapy alone may be convenient and cost-effective management strategy in uncomplicated traumatic hyphema.

摘要

目的

比较局部应用皮质类固醇联合支持治疗与单纯支持治疗外伤性前房积血的疗效。

患者与方法

在这项回顾性研究中,206例患者被分为两组;第一组,98只眼接受局部皮质类固醇治疗(12×1)及支持治疗,包括卧床休息、头部抬高(45度)和补液。第二组,108只眼仅接受支持治疗。评估前房积血大小、初始和最终视力及眼压、前房积血清除时间和再出血发生率。

结果

两组前房积血吸收所需时间分别为60.25±33.9小时和62.3±28.9小时(P=0.62)。局部皮质类固醇组(4.01%)和非类固醇组(6.48%)的再出血率无显著差异(P=0.67)。两组的初始和最终视力相似(P=0.86)。在第一组和第二组中,平均眼压分别为19.7±8.01和14.2±10.2 mmHg。两组间差异具有统计学意义(P=0.04)。

结论

与单纯接受支持治疗的患者相比,接受局部皮质类固醇治疗的患者发生再出血或视力不佳的可能性并不更低。对于无并发症的外伤性前房积血,单纯支持治疗可能是一种方便且经济有效的治疗策略。

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