Nomura Fuminori, Kishimoto Seiji
Department of Head and Neck Surgery, Tokyo Medical and Dental University, Japan.
Department of Head and Neck Surgery, Tokyo Medical and Dental University, Japan.
Auris Nasus Larynx. 2014 Dec;41(6):572-5. doi: 10.1016/j.anl.2014.07.001. Epub 2014 Sep 8.
Synovial sarcoma in the head and neck region is rare, and is difficult to resect with adequate safety margins because of its anatomical complexity. We herein report our experiences with synovial sarcoma in this region, and review the literature regarding the management of such cases.
We retrospectively examined four cases of synovial sarcoma arising from the temporomandibular joint (TMJ) area and infratemporal fossa.
Only one patient remains alive without disease, while the other three patients have died.
The local control of these tumors has improved because of the progress in the surgical operation methods, while it is expected that there is still a high rate of deaths due to distant metastasis increase. The development of strong chemotherapy is needed for the use after the initial treatment and surgery.
头颈部滑膜肉瘤较为罕见，由于其解剖结构复杂，难以在安全切缘足够的情况下进行切除。我们在此报告我们在该区域滑膜肉瘤方面的经验，并回顾有关此类病例管理的文献。
我们回顾性研究了4例起源于颞下颌关节（TMJ）区域和颞下窝的滑膜肉瘤病例。
仅1例患者无病存活，其他3例患者均已死亡。
由于手术操作方法的进步，这些肿瘤的局部控制有所改善，但预计仍因远处转移增加而导致较高的死亡率。初始治疗和手术后需要开发强效化疗药物以供使用。
