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[肺部立体定向放射治疗后肿瘤反应的放射学评估]

[Radiological evaluation of the tumour response after lung stereotactic radiotherapy].

作者信息

Vulquin N, Feutray S, Peignaux-Casasnovas K, Humbert O, Créhange G, Truc G, Maingon P, Martin E

机构信息

Département de radiothérapie, centre Georges-François-Leclerc, 1, rue du Professeur-Marion, BP 77980, 21079 Dijon cedex, France.

Département de radiologie, centre Georges-François-Leclerc, 1, rue du Professeur-Marion, 21079 Dijon cedex, France.

出版信息

Cancer Radiother. 2014 Oct;18(5-6):414-9. doi: 10.1016/j.canrad.2014.07.157. Epub 2014 Sep 16.

Abstract

Stereotactic body radiotherapy is the treatment of choice for medically non-operable T1-T2 N0M0 non-small cell lung cancer or for slowly growing lung metastases with no evolutive primary tumour. Lung stereotactic radiotherapy provides an excellent local control rate, higher than 80%. Nevertheless, although the clinical toxicity rate is less than 5%, postradiation radiological reactions surrounding the tumour, called "radiological radiation pneumonitis", are very frequent, which makes it difficult to evaluate the tumour response. Firstly, this review describes the lesions of acute and chronic radiation pneumonitis and the CT images suggesting a local recurrence. Then, we evaluated the place of PET after stereotactic body radiotherapy in the follow-up period. Finally, we suggest an algorithm helping physicians in the follow-up of such treated patients.

摘要

立体定向体部放射治疗是医学上无法手术的T1-T2 N0M0非小细胞肺癌或无进展性原发肿瘤的缓慢生长肺转移瘤的首选治疗方法。肺部立体定向放射治疗可提供高于80%的出色局部控制率。然而,尽管临床毒性率低于5%,但肿瘤周围的放射后放射学反应,即“放射性放射性肺炎”却非常常见,这使得评估肿瘤反应变得困难。首先,本综述描述了急性和慢性放射性肺炎的病变以及提示局部复发的CT图像。然后,我们评估了立体定向体部放射治疗后PET在随访期的作用。最后,我们提出一种算法,以帮助医生对接受此类治疗的患者进行随访。

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