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《精神疾病诊断与统计手册》第5版中青少年限制性饮食失调症患者1年预后的预测因素:全国饮食失调症质量改进协作组报告

Predictors of outcome at 1 year in adolescents with DSM-5 restrictive eating disorders: report of the national eating disorders quality improvement collaborative.

作者信息

Forman Sara F, McKenzie Nicole, Hehn Rebecca, Monge Maria C, Kapphahn Cynthia J, Mammel Kathleen A, Callahan S Todd, Sigel Eric J, Bravender Terrill, Romano Mary, Rome Ellen S, Robinson Kelly A, Fisher Martin, Malizio Joan B, Rosen David S, Hergenroeder Albert C, Buckelew Sara M, Jay M Susan, Lindenbaum Jeffrey, Rickert Vaughn I, Garber Andrea, Golden Neville H, Woods Elizabeth R

机构信息

Division of Adolescent/Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts.

Division of Adolescent/Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts.

出版信息

J Adolesc Health. 2014 Dec;55(6):750-6. doi: 10.1016/j.jadohealth.2014.06.014. Epub 2014 Sep 4.

Abstract

PURPOSE

The National Eating Disorders Quality Improvement Collaborative evaluated data of patients with restrictive eating disorders to analyze demographics of diagnostic categories and predictors of weight restoration at 1 year.

METHODS

Fourteen Adolescent Medicine eating disorder programs participated in a retrospective review of 700 adolescents aged 9-21 years with three visits, with DSM-5 categories of restrictive eating disorders including anorexia nervosa (AN), atypical AN, and avoidant/restrictive food intake disorder (ARFID). Data including demographics, weight and height at intake and follow-up, treatment before intake, and treatment during the year of follow-up were analyzed.

RESULTS

At intake, 53.6% met criteria for AN, 33.9% for atypical AN, and 12.4% for ARFID. Adolescents with ARFID were more likely to be male, younger, and had a longer duration of illness before presentation. All sites had a positive change in mean percentage median body mass index (%MBMI) for their population at 1-year follow-up. Controlling for age, gender, duration of illness, diagnosis, and prior higher level of care, only %MBMI at intake was a significant predictor of weight recovery. In the model, there was a 12.7% change in %MBMI (interquartile range, 6.5-19.3). Type of treatment was not predictive, and there were no significant differences between programs in terms of weight restoration.

CONCLUSIONS

The National Eating Disorders Quality Improvement Collaborative provides a description of the patient population presenting to a national cross-section of 14 Adolescent Medicine eating disorder programs and categorized by DSM-5. Treatment modalities need to be further evaluated to assess for more global aspects of recovery.

摘要

目的

全国饮食失调质量改进协作组评估了患有限制性饮食失调患者的数据,以分析诊断类别的人口统计学特征以及1年后体重恢复的预测因素。

方法

14个青少年医学饮食失调项目参与了一项对700名9至21岁青少年的回顾性研究,这些青少年接受了三次就诊,其诊断依据为《精神疾病诊断与统计手册》第5版中限制性饮食失调的类别,包括神经性厌食症(AN)、非典型AN和回避/限制性食物摄入障碍(ARFID)。分析的数据包括人口统计学特征、入院时和随访时的体重与身高、入院前的治疗以及随访年度内的治疗情况。

结果

入院时,53.6%符合AN标准,33.9%符合非典型AN标准,12.4%符合ARFID标准。患有ARFID的青少年更可能为男性、年龄更小,且在就诊前患病时间更长。在1年随访时,所有研究点人群的平均百分比中位数体重指数(%MBMI)均有正向变化。在控制了年龄、性别、病程、诊断以及先前更高水平的护理因素后,仅入院时的%MBMI是体重恢复的显著预测因素。在该模型中,%MBMI有12.7%的变化(四分位间距为6.5 - 19.3)。治疗类型并无预测作用,且各项目在体重恢复方面无显著差异。

结论

全国饮食失调质量改进协作组描述了向14个青少年医学饮食失调项目的全国性样本就诊并按照《精神疾病诊断与统计手册》第5版分类的患者群体。治疗方式需要进一步评估,以全面评估康复情况。

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