Guarneri F, Cannavò S P, Minciullo P L, Gangemi S
Dermatology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
J Eur Acad Dermatol Venereol. 2015 Jan;29(1):21-5. doi: 10.1111/jdv.12701. Epub 2014 Sep 8.
More than 200 years after first description and 150 years after complete definition by Gibert, pityriasis rosea (PR) is still a clinical entity with many obscure aspects. Although great interest was focused on aetiology, studies on immunological mechanisms associated with this disease were rather discontinuous. We present a review of the literature on immunological features of PR, aimed to outline a unified picture of currently available knowledge in this field and create a useful starting point for future research.