在印度北部的亚洲印度人群中，高体脂和低肌肉量与动脉僵硬度增加有关。

High body fat and low muscle mass are associated with increased arterial stiffness in Asian Indians in North India.

作者信息

Anoop Shajith, Misra Anoop, Bhardwaj Swati, Gulati Seema

机构信息

Center of Nutrition & Metabolic Research (C-NET), National Diabetes, Obesity and Cholesterol Foundation (N-DOC), SDA, New Delhi, India; Diabetes Foundation (India), SDA, New Delhi.

Center of Nutrition & Metabolic Research (C-NET), National Diabetes, Obesity and Cholesterol Foundation (N-DOC), SDA, New Delhi, India; Diabetes Foundation (India), SDA, New Delhi; Fortis C-DOC Centre of Excellence for Diabetes, Metabolic Diseases and Endocrinology, Chirag Enclave, Nehru place, New Delhi; Fortis Flt. Lt. Rajan Dhall Hospital, Vasant Kunj, New Delhi, India.

出版信息

J Diabetes Complications. 2015 Jan-Feb;29(1):38-43. doi: 10.1016/j.jdiacomp.2014.08.001. Epub 2014 Aug 8.

DOI:10.1016/j.jdiacomp.2014.08.001

PMID:25200813

Abstract

AIM

To investigate the associations of high body fat and low muscle mass with arterial stiffness in Asian Indians with type 2 diabetes mellitus (T2DM) in North India.

METHODS

In this cross sectional study, subjects with T2DM (males n=110, females n=58, mean age: 53.8±10.0years) were recruited. Anthropometry and body composition analysis were performed and measures of glycemia, lipids and PWV were analyzed.

RESULTS

Significant positive correlation was observed between PWV and body fat (p<0.05), left leg fat (p<0.05), and right leg fat (p<0.01) percentages only in females. In males, significant negative correlation was observed between PWV and truncal fat free mass (p<0.05) and fat free mass in right arm (p=0.05) and left arm (p<0.05). In both males and females, significant negative correlation was observed between PWV and fat free mass in left leg (p<0.01) and for right leg fat free mass only in females.

CONCLUSION

Excess adiposity and low fat free mass are associated with arterial stiffening in Asian Indians with T2DM in North India, with significant gender differences.

摘要

目的

调查印度北部2型糖尿病（T2DM）亚洲印度人中高体脂和低肌肉量与动脉僵硬度之间的关联。

方法

在这项横断面研究中，招募了T2DM患者（男性n = 110，女性n = 58，平均年龄：53.8±10.0岁）。进行人体测量和身体成分分析，并分析血糖、血脂和脉搏波速度（PWV）的测量值。

结果

仅在女性中，观察到PWV与体脂百分比（p<0.05）、左腿脂肪百分比（p<0.05）和右腿脂肪百分比（p<0.01）之间存在显著正相关。在男性中，观察到PWV与躯干去脂体重（p<0.05）、右臂去脂体重（p = 0.05）和左臂去脂体重（p<0.05）之间存在显著负相关。在男性和女性中，均观察到PWV与左腿去脂体重之间存在显著负相关（p<0.01），且仅在女性中观察到PWV与右腿去脂体重之间存在显著负相关。