Asselmann Eva, Wittchen Hans-Ulrich, Lieb Roselind, Beesdo-Baum Katja
Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany,
Eur Child Adolesc Psychiatry. 2015 Apr;24(4):451-61. doi: 10.1007/s00787-014-0596-x. Epub 2014 Sep 9.
This study aims to examine whether (a) low child valence (emotional connectedness) within the mother-child relationship increases the risk for offspring depression, (b) low child potency (individual autonomy) increases the risk for offspring anxiety, and (c) maternal psychopathology pronounces these associations. We used data from a prospective-longitudinal study of adolescents (aged 14-17 at baseline) and their mothers (N = 1,015 mother-child dyads). Anxiety disorders and depression were assessed repeatedly over 10 years in adolescents (T0, T1, T2, T3) and their mothers (T1, T3) using the DSM-IV/M-CIDI. Valence and potency were assessed in mothers (T1) with the Subjective Family Image Questionnaire. Odds ratios (OR) from logistic regression were used to estimate associations between low child valence/potency and offspring psychopathology (cumulated lifetime incidences; adjusted for sex and age). In separate models (low valence or low potency as predictor), low child valence predicted offspring depression only (OR = 1.26 per SD), while low child potency predicted offspring anxiety (OR = 1.24) and depression (OR = 1.24). In multiple models (low valence and low potency as predictors), low child valence predicted offspring depression only (OR = 1.19), while low child potency predicted offspring anxiety only (OR = 1.22). Low child potency interacted with maternal anxiety on predicting offspring depression (OR = 1.49), i.e. low child potency predicted offspring depression only in the presence of maternal anxiety (OR = 1.33). These findings suggest that low child valence increases the risk for offspring depression, while low child potency increases the risk for offspring anxiety and depression and interacts with maternal psychopathology on predicting offspring depression.
（a）母婴关系中低儿童效价（情感联结）是否会增加后代患抑郁症的风险；（b）低儿童效能（个体自主性）是否会增加后代患焦虑症的风险；（c）母亲的精神病理学是否会强化这些关联。我们使用了一项针对青少年（基线年龄为14 - 17岁）及其母亲（N = 1015对母婴二元组）的前瞻性纵向研究数据。使用DSM-IV/M - CIDI在10年期间对青少年（T0、T1、T2、T3）及其母亲（T1、T3）反复评估焦虑症和抑郁症。使用主观家庭形象问卷对母亲（T1）进行效价和效能评估。逻辑回归的比值比（OR）用于估计低儿童效价/效能与后代精神病理学（累积终生发病率；按性别和年龄调整）之间的关联。在单独的模型中（以低效价或低效能作为预测因素），低儿童效价仅预测后代抑郁症（每标准差OR = 1.26），而低儿童效能预测后代焦虑症（OR = 1.24）和抑郁症（OR = 1.24）。在多个模型中（以低效价和低效能作为预测因素），低儿童效价仅预测后代抑郁症（OR = 1.19），而低儿童效能仅预测后代焦虑症（OR = 1.22）。低儿童效能与母亲焦虑在预测后代抑郁症方面存在交互作用（OR = 1.49），即低儿童效能仅在母亲存在焦虑的情况下预测后代抑郁症（OR = 1.33）。这些发现表明，低儿童效价会增加后代患抑郁症的风险，而低儿童效能会增加后代患焦虑症和抑郁症的风险，并且在预测后代抑郁症方面与母亲的精神病理学存在交互作用。
