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儿科风湿病:全身型幼年特发性关节炎中巨噬细胞活化综合征的诊断。

Paediatric rheumatic disease: Diagnosing macrophage activation syndrome in systemic JIA.

机构信息

Center for Molecular and Cellular Intervention, Department of Pediatric Rheumatology and Immunology, University Medical Center Utrecht, PO Box 85090, 3508 AB Utrecht, Netherlands.

出版信息

Nat Rev Rheumatol. 2014 Nov;10(11):640-2. doi: 10.1038/nrrheum.2014.143. Epub 2014 Sep 9.

Abstract

Macrophage activation syndrome (MAS) in systemic juvenile idiopathic arthritis (sJIA) is difficult to distinguish from active sJIA or sepsis. A collaborative effort scoring the performance of different clinical diagnostic criteria provides valuable guidance to clinicians, but challenges in the diagnosis of sJIA-related MAS remain.

摘要

巨噬细胞活化综合征(MAS)在全身型幼年特发性关节炎(sJIA)中难以与活动期 sJIA 或脓毒症相鉴别。协作式评分努力对不同临床诊断标准的性能进行评分,为临床医生提供了有价值的指导,但 sJIA 相关 MAS 的诊断仍然存在挑战。

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