Center for Molecular and Cellular Intervention, Department of Pediatric Rheumatology and Immunology, University Medical Center Utrecht, PO Box 85090, 3508 AB Utrecht, Netherlands.
Nat Rev Rheumatol. 2014 Nov;10(11):640-2. doi: 10.1038/nrrheum.2014.143. Epub 2014 Sep 9.
Macrophage activation syndrome (MAS) in systemic juvenile idiopathic arthritis (sJIA) is difficult to distinguish from active sJIA or sepsis. A collaborative effort scoring the performance of different clinical diagnostic criteria provides valuable guidance to clinicians, but challenges in the diagnosis of sJIA-related MAS remain.
巨噬细胞活化综合征(MAS)在全身型幼年特发性关节炎(sJIA)中难以与活动期 sJIA 或脓毒症相鉴别。协作式评分努力对不同临床诊断标准的性能进行评分,为临床医生提供了有价值的指导,但 sJIA 相关 MAS 的诊断仍然存在挑战。