A cosmesis outcome substudy in a prospective, randomized trial comparing radioguided seed localization with standard wire localization for nonpalpable, invasive, and in situ breast carcinomas.
作者信息
Parvez Elena, Cornacchi Sylvie D, Hodgson Nicole, Thoma Achilleas, Kong Iwa, Foster Gary, Cheng Ji, Goldsmith Charlie H, Dao Dyda, Lovrics Peter J
机构信息
Department of Surgery, McMaster University, Hamilton, ON, Canada.
Department of Surgery, McMaster University, Hamilton, ON, Canada; Department of Surgical Oncology, Hamilton Health Sciences and Juravinski Hospital and Cancer Centre, Hamilton, ON, Canada; Department of Oncology, Hamilton Health Sciences and Juravinski Hospital and Cancer Centre, Hamilton, ON, Canada.
出版信息
Am J Surg. 2014 Nov;208(5):711-718. doi: 10.1016/j.amjsurg.2014.05.030. Epub 2014 Aug 5.
BACKGROUND
The primary study objective was to compare the cosmetic result of radioguided seed localization (RSL) with wire localization (WL).
METHODS
A subgroup of patients enrolled in a multicentered, randomized trial comparing WL with RSL participated. Frontal photographs were taken 1 and 3 years postsurgery. The European Organization for Research and Treatment of Cancer Cosmetic Rating System was used to evaluate cosmesis outcomes by the patient and a panel of 5 raters.
RESULTS
The study enrolled 73 patients (WL, n = 38; RSL, n = 35). Most patients rated their overall cosmesis as "excellent" or "good" (76% WL, 80% RSL). Patient and panel ratings on all cosmetic outcomes were similar between groups. Multivariable regression for overall cosmesis found larger specimen volume and reoperation to be predictors of worse ratings.
CONCLUSIONS
All cosmetic outcomes assessed were similar after WL and RSL. The comparable outcomes may reflect similar reoperation rates and volumes of excision between groups.
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