Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
Department of Health Technology and Services research, University of Twente, Enschede, The Netherlands.
PLoS One. 2020 May 13;15(5):e0232690. doi: 10.1371/journal.pone.0232690. eCollection 2020.
Current localization techniques used in breast conserving surgery for non-palpable tumors show several disadvantages. Magnetic Seed Localization (MSL) is an innovative localization technique aiming to overcome these disadvantages. This study evaluated the expected budget impact of adopting MSL compared to standard of care.
Standard of care with Wire-Guided Localization (WGL) and Radioactive Seed Localization (RSL) use was compared with a future situation gradually adopting MSL next to RSL or WGL from a Dutch national perspective over 5 years (2017-2022). The intervention costs for WGL, RSL and MSL and the implementation costs for RSL and MSL were evaluated using activity-based costing in eight Dutch hospitals. Based on available list prices the price of the magnetic seed was ranged €100-€500.
The intervention costs for WGL, RSL and MSL were respectively: €2,617, €2,834 and €2,662 per patient and implementation costs were €2,974 and €26,826 for MSL and RSL respectively. For standard of care the budget impact increased from €14.7m to €16.9m. Inclusion of MSL with a seed price of €100 showed a budget impact of €16.7m. Above a price of €178 the budget impact increased for adoption of MSL, rising to €17.6m when priced at €500.
MSL could be a cost-efficient localization technique in resecting non-palpable tumors in the Netherlands. The online calculation model can inform adoption decisions internationally. When determining retail price of the magnetic seed, cost-effectiveness should be considered.
目前用于非可触及肿瘤保乳手术的定位技术存在一些缺点。磁性种子定位(MSL)是一种创新的定位技术,旨在克服这些缺点。本研究评估了与标准护理相比采用 MSL 的预期预算影响。
从荷兰国家角度来看,在 5 年内(2017-2022 年),比较了标准护理(使用 Wire-Guided Localization [WGL] 和 Radioactive Seed Localization [RSL])与逐步采用 MSL 与 RSL 或 WGL 相结合的未来情况。使用基于活动的成本核算在八家荷兰医院评估了 WGL、RSL 和 MSL 的干预成本以及 RSL 和 MSL 的实施成本。根据现有标价,磁种子的价格范围为€100-€500。
WGL、RSL 和 MSL 的干预成本分别为:€2617、€2834 和€2662 每例患者,实施成本分别为€2974 和€26826 用于 MSL 和 RSL。对于标准护理,预算影响从€14.7m 增加到€16.9m。在 MSL 中纳入价格为€100 的种子显示预算影响为€16.7m。当价格高于€178 时,采用 MSL 的预算影响会增加,当价格定为€500 时,预算影响上升至€17.6m。
MSL 可能是荷兰切除非可触及肿瘤的一种具有成本效益的定位技术。在线计算模型可以为国际采用决策提供信息。在确定磁性种子的零售价格时,应考虑成本效益。