Carle Foundation Hospital, Urbana, IL, USA.
University of Illinois - Urbana/Champaign, Champaign, IL, USA.
Ann Surg Oncol. 2018 Jan;25(1):131-136. doi: 10.1245/s10434-017-6102-1. Epub 2017 Nov 13.
Radioactive seed localization (RSL) is a safe and effective alternative to wire localization (WL) for nonpalpable breast lesions. While several large academic institutions currently utilize RSL, few community hospitals have adopted this technique.
The aim of this study was to examine the experience of RSL versus WL at a large community hospital.
A retrospective chart review of patients who underwent RSL or WL for breast-conserving surgery from 1 November 2013 to 31 November 2015.
The total number of lesions examined was 382. RSL was utilized in 205 (54%) lesions, with 187 undergoing single RSL, while WL was used in 155 (40%) lesions, with 109 undergoing single WL; both techniques were used in 22 (6%) lesions. Pathology was benign in 142 (48%) lesions, with 93 RSLs and 49 WLs. For malignant lesions, mean specimen size was 36.3 g for single RSL and 35.9 g for single WL (p = 0.904). Re-excision for margin clearance was required for 16 (17%) malignant lesions in the RSL group and 10 (17%) in the WL group (p = 0.954). For malignant lesions, mean operating room time was 86 min for single RSL versus 70 min for single WL (p = 0.014).
The use of RSL is a viable option in the community setting, with several benefits over WL. While operative times were slightly longer with RSL, there was no difference in specimen size or re-excision rate for malignant lesions.
放射性种子定位(RSL)是一种安全有效的替代不可触及乳房病变的金属丝定位(WL)的方法。虽然有几个大型学术机构目前使用 RSL,但很少有社区医院采用这种技术。
本研究旨在研究一家大型社区医院 RSL 与 WL 的经验。
对 2013 年 11 月 1 日至 2015 年 11 月 31 日期间接受保乳手术的 RSL 或 WL 患者进行回顾性图表审查。
共检查了 382 个病变。RSL 用于 205 个(54%)病变,其中 187 个病变进行了单次 RSL,而 WL 用于 155 个(40%)病变,其中 109 个病变进行了单次 WL;两种技术均用于 22 个(6%)病变。142 个(48%)病变的病理结果为良性,其中 93 个 RSL 和 49 个 WL。对于恶性病变,单次 RSL 的标本平均大小为 36.3g,单次 WL 的标本平均大小为 35.9g(p=0.904)。RSL 组有 16 个(17%)恶性病变需要再次切除以清除边缘,WL 组有 10 个(17%)恶性病变需要再次切除(p=0.954)。对于恶性病变,单次 RSL 的手术时间平均为 86 分钟,而单次 WL 的手术时间平均为 70 分钟(p=0.014)。
RSL 在社区环境中是一种可行的选择,与 WL 相比具有多项优势。虽然 RSL 的手术时间略长,但恶性病变的标本大小或再次切除率没有差异。