Di Donato Nadine, Montanari Giulia, Benfenati Arianna, Leonardi Debora, Bertoldo Valentina, Monti Giorgia, Raimondo Diego, Seracchioli Renato
Minimally Invasive Gynaecological Surgery Unit, S.Orsola-Malpighi Hospital, University of Bologna, Via Massarenti, 13, 40138, Bologna, Italy.
Minimally Invasive Gynaecological Surgery Unit, S.Orsola-Malpighi Hospital, University of Bologna, Via Massarenti, 13, 40138, Bologna, Italy.
Eur J Obstet Gynecol Reprod Biol. 2014 Oct;181:289-93. doi: 10.1016/j.ejogrb.2014.08.016. Epub 2014 Aug 15.
OBJECTIVE(S): To evaluate the prevalence of adenomyosis in patients undergoing surgery for endometriosis.
Retrospective study including 1618 women with preoperative clinical and ultrasound diagnosis of endometriosis. As preoperative assessment, all patients underwent ultrasound to assess endometriosis and all features associated with adenomyosis (heterogeneous myometrial echotexture, globular-appearing uterus, asymmetrical thickness of anteroposterior wall of the myometrium, subendometrial myometrial cysts, subendometrial echogenic linear striations or poor definition of the endometrial-myometrial junction).
Adenomyosis was present in 353/1618 (21.8%) women included in the study. Multivariate analysis showed that the prevalence of adenomyosis was significantly associated with deep infiltrating endometriosis, parity, dysmenorrhea intensity and women's age (P<0.0001).
CONCLUSION(S): Adenomyosis is a common condition but its aetiology and natural history are still unknown. Our experience showed a 21.8% of prevalence of adenomyosis in patients affected by endometriosis and its association with parous women, increasing age, dysmenorrhea intensity and with the presence of deep infiltrating endometriosis.
评估接受子宫内膜异位症手术患者的子宫腺肌病患病率。
回顾性研究，纳入1618例术前经临床及超声诊断为子宫内膜异位症的女性。作为术前评估，所有患者均接受超声检查以评估子宫内膜异位症及所有与子宫腺肌病相关的特征（肌层回声不均匀、子宫呈球形、肌层前后壁厚度不对称、内膜下肌层囊肿、内膜下强回声线性条纹或内膜-肌层交界不清）。
本研究纳入的1618例女性中，353例（21.8%）存在子宫腺肌病。多因素分析显示，子宫腺肌病的患病率与深部浸润性子宫内膜异位症、产次、痛经强度及女性年龄显著相关（P<0.0001）。
子宫腺肌病是一种常见疾病，但其病因及自然史仍不清楚。我们的经验显示，子宫内膜异位症患者中子宫腺肌病的患病率为21.8%，且其与经产妇、年龄增加、痛经强度及深部浸润性子宫内膜异位症的存在有关。
