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心脏麻醉中的高位胸椎硬膜外麻醉:综述

High thoracic epidural in cardiac anesthesia: a review.

作者信息

Jakobsen Carl-Johan

机构信息

Aarhus University Hospital, Aarhus N, Denmark

出版信息

Semin Cardiothorac Vasc Anesth. 2015 Mar;19(1):38-48. doi: 10.1177/1089253214548764. Epub 2014 Sep 7.

Abstract

High thoracic epidural analgesia (HTEA) offers a distinctive opportunity to enhance postoperative recovery for the thoracic surgery patient. In the modern hospital setting with day of admission surgery, the logistics of insertion of the epidural catheter has become increasingly difficult. The greatest limitation to its use might be the believed increased risk of epidural hematoma associated with anticoagulation during cardiopulmonary bypass. The aim of this review is to give an overview of complications and effect on outcomes with focus on cardiac performance and postoperative glycemic control and kidney function. Patients with epidurals may have improved postoperative pulmonary function and shorter ventilation time, while impact on length of stay in the intensive care unit and hospital is not as evident. HTEA is effective in pain management, attenuates perioperative stress and seems to improve postoperative blood glucose control. Whether HTEA improves recovery and facilitates fast-track is still to be confirmed. With regard to serious postoperative complications, there is evidence of reduction in supraventricular arrhythmias and lower frequency of postoperative acute kidney injury and dialysis. There are some indications of lower short term mortality and frequency of postoperative myocardial infarctions, but only as a combined outcome. The present short-term mortality of 1% to 2% should be compared with the most pessimistic frequency of epidural hematoma being 1 in 4600 patients.

摘要

高位胸椎硬膜外镇痛(HTEA)为促进胸外科手术患者术后恢复提供了独特的机会。在现代医院中,由于入院当天就进行手术,硬膜外导管的插入操作在后勤安排上变得越来越困难。其使用的最大限制可能是人们认为在体外循环期间抗凝会增加硬膜外血肿的风险。本综述的目的是概述并发症以及对结局的影响,重点关注心脏功能、术后血糖控制和肾功能。接受硬膜外镇痛的患者术后肺功能可能改善,通气时间缩短,而对重症监护病房和医院住院时间的影响并不明显。HTEA在疼痛管理方面有效,可减轻围手术期应激,且似乎能改善术后血糖控制。HTEA是否能促进恢复并推动快速康复仍有待证实。关于严重的术后并发症,有证据表明室上性心律失常减少,术后急性肾损伤和透析的发生率降低。有一些迹象表明短期死亡率和术后心肌梗死的发生率较低,但只是作为综合结果。目前1%至2%的短期死亡率应与硬膜外血肿最悲观的发生率(每4600例患者中有1例)进行比较。

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