Müller Simon, Ebnöther Myriam, Itin Peter
Department of Dermatology, University Hospital Basel, Basel, Switzerland.
Case Rep Dermatol. 2014 Jul 19;6(2):180-4. doi: 10.1159/000365863. eCollection 2014 May.
Green nail syndrome (GNS) caused by Pseudomonas aeruginosa is the most common bacterial nail infection. The treatment of GNS is challenging in many cases and recommendations based on clinical trials are lacking. We report two cases with GNS successfully treated with off-label use of topical nadifloxacin, a fluoroquinolone approved for acne and bacterial skin infections in some countries.
由铜绿假单胞菌引起的绿甲综合征(GNS)是最常见的细菌性甲感染。在许多情况下,GNS的治疗具有挑战性,且缺乏基于临床试验的推荐。我们报告了两例GNS患者,通过外用那氟沙星(一种在一些国家被批准用于治疗痤疮和细菌性皮肤感染的氟喹诺酮类药物)的超说明书用药成功治愈。