Michaelis O E, Carswell N, Velasquez M T, Hansen C T
Beltsville Human Nutrition Research Center, Agriculture Research Service, Maryland.
Nutrition. 1989 Jan-Feb;5(1):56-9.
The Spontaneous Hypertensive/NIH-corpulent rat is a recently developed genetic model of obesity and diabetes. The strain exhibits both metabolic and histopathological characteristics associated with non-insulin dependent diabetes mellitus in humans. This rodent model is unique in that glucose intolerance is expressed in both sexes and in both phenotypes.
自发性高血压/国立卫生研究院肥胖大鼠是一种最近开发的肥胖和糖尿病遗传模型。该品系表现出与人类非胰岛素依赖型糖尿病相关的代谢和组织病理学特征。这种啮齿动物模型的独特之处在于，葡萄糖不耐受在两性和两种表型中均有表现。
