Maruyama T, Nomiyama T, Asahi M, Mori N, Ono E, Kawahara A, Fujimoto S
Department of Dermatology, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Japan.
Histol Histopathol. 1989 Jan;4(1):85-94.
Based on ultrastructural features of cellular components of a hemangiopericytoma, hyperplastic cells are classifiable into fibroblast-like (group I), endotheloid (group II) and pericyte-like (group III) cells. The transformation of the group I cells to the group II, or to the group III cells, is pronounced in our electron micrographs and this may imply that the group I cell is the principal cell of origin in this neoplasm. The smooth muscle-like (group IV) cells comprising the media of the arteries and veins in this neoplasm may represent modified, possibly de-differentiated smooth muscle cells reacted to the neoplastic proliferation of the surrounding adventitial (group I) cells.
基于血管外皮细胞瘤细胞成分的超微结构特征，增生细胞可分为成纤维细胞样（I组）、内皮样（II组）和周细胞样（III组）细胞。在我们的电子显微镜照片中，I组细胞向II组或III组细胞的转变很明显，这可能意味着I组细胞是这种肿瘤的主要起源细胞。构成该肿瘤中动脉和静脉中膜的平滑肌样（IV组）细胞可能代表对周围外膜（I组）细胞的肿瘤性增殖起反应的修饰的、可能去分化的平滑肌细胞。
