Kolomiets O L
Arkh Patol. 1975;37(8):53-60.
Electron-microscopy studies of malignant low-differentiated hemangiopericytomas, induced by adenovirus of monkeys SA7(C8) and bovine adenovirus type 3 were, carried out. At earlier stages of the development of these tumours in tumourous cells located around capillaries there were observed the ultrastructural characteristics typical of pericytes and cells of human hemangiopericytis: the presence of the basal layer and fibrills as thick as 40 A. As differentiation proceeded, tumorous cells acquired an elongated form, and in some of them there appeared myofilaments typical of smooth-muscle cells, with local thickenings, as well as multitude of pinicytic vacules along the plasmatic membranes of cells. The foregoing confirms the assumption of hemangiopericytomas as a prestage of leio-(angioleio-) myosarcomas. Moreover, the tumour cells revealed the presence of cilia, fibrills as thick as 100A, 75A, annulate lamelae, and myelin-like formations.
对由猴SA7（C8）腺病毒和牛3型腺病毒诱导产生的恶性低分化血管外皮细胞瘤进行了电子显微镜研究。在这些肿瘤发展的早期阶段，在毛细血管周围的肿瘤细胞中观察到了周细胞和人类血管外皮细胞瘤细胞典型的超微结构特征：存在基底层和直径达40埃的纤维。随着分化的进行，肿瘤细胞呈细长形，其中一些出现了平滑肌细胞典型的肌丝，伴有局部增厚，并且细胞浆膜沿线有大量饮液泡。上述情况证实了血管外皮细胞瘤是平滑（血管平滑）肌肉瘤前期阶段的假设。此外，肿瘤细胞显示存在纤毛、直径达100埃、75埃的纤维、环层板和髓鞘样结构。
