铜催化的sp(2) C-H键磷酸化反应。
Copper-catalyzed phosphorylation of sp(2) C-H bonds.
作者信息
Wang Shan, Guo Rui, Wang Gao, Chen Shan-Yong, Yu Xiao-Qi
机构信息
Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, P. R. China.
出版信息
Chem Commun (Camb). 2014 Oct 28;50(84):12718-21. doi: 10.1039/c4cc06246a.
PMID:25204577
Abstract
The phosphorylation of the ortho C-H bonds in benzamides containing an 8-aminoquinoline moiety as a bidentate directing group with H-phosphonates using copper as a catalyst under mild temperature conditions is described. This method shows high functional group compatibility and selectively gives mono-substituted products.
摘要
描述了在温和温度条件下，以含8-氨基喹啉部分作为双齿导向基团的苯甲酰胺中的邻位C-H键与H-膦酸酯，使用铜作为催化剂进行磷酸化反应。该方法显示出高官能团兼容性，并选择性地得到单取代产物。
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