肾小管疾病中锝-99m二巯基丁二酸和锝-99m依替菲宁的摄取差异：两例报告并文献复习

Reddy Gorla Arun Kumar, Agrawal Kanhaiyalal, Sood Ashwani, Bhattacharya Anish, Mittal Bhagwant Rai

Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, Punjab and Haryana, India.

Indian J Nucl Med. 2014 Jul;29(3):160-2. doi: 10.4103/0972-3919.136571.

Tc-99m DMSA and Tc-99m EC studies are invaluable functional imaging modalities for renal structural and functional assessment. Normally, the relative renal function estimated by the two methods correlates well with each other. We here present two patients with renal tubular acidosis who showed impaired/altered DMSA uptake with normal EC renal dynamic study depicting the pitfall of DMSA imaging in tubular disorders. The two presented cases also depict distinct pattern of Tc-99m DMSA scintigraphic findings in patients with proximal and distal renal tubular acidosis, thus highlighting the factors affecting DMSA kinetics.

锝-99m二巯基丁二酸（Tc-99m DMSA）和锝-99m依他苯酯（Tc-99m EC）检查是用于肾脏结构和功能评估的非常有价值的功能成像方法。正常情况下，通过这两种方法估算的相对肾功能彼此相关性良好。我们在此展示两名肾小管酸中毒患者，他们表现出DMSA摄取受损/改变，而EC肾动态检查正常，这显示了DMSA成像在肾小管疾病中的缺陷。所展示的这两个病例还描绘了近端和远端肾小管酸中毒患者Tc-99m DMSA闪烁显像结果的不同模式，从而突出了影响DMSA动力学的因素。