Meliones J N, Snider A R, Serwer G A, Shaffer E M, Rocchini A P, Beekman R H, Rosenthal A, Dick M, Peters J, Reynolds P
Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor 48109.
Am J Cardiol. 1989 Jan 15;63(3):231-6. doi: 10.1016/0002-9149(89)90291-9.
To assess left ventricular (LV) diastolic filling in children with pressure overload hypertrophy, 12 patients with LV outflow obstruction (7 with aortic valve stenosis and 5 with aortic coarctation) and 12 healthy, age-matched control subjects were examined. Each child underwent M-mode echocardiography and pulsed Doppler examination of the LV inflow. The patients with LV outflow obstruction had cardiac catheterization and balloon angioplasty. Their echo/Doppler examinations were performed in the catheterization laboratory before and immediately after balloon angioplasty. From the M-mode echocardiogram, the LV cavity dimensions and wall thicknesses, LV mass and shortening fraction were measured. The following measurements were made from the Doppler recording: peak velocities at rapid ventricular filling (peak E) and during atrial contraction (peak A), ratio of peak E to peak A velocities, total area under the Doppler curve, percent of the total Doppler area occurring in the first one-third of diastole (0.33 area fraction), percent of the total area occurring under the E wave (E area fraction), percent of the total area occurring under the A wave (A area fraction) and the ratio of E area to A area.(ABSTRACT TRUNCATED AT 250 WORDS)
为评估压力负荷过重性肥厚患儿的左心室（LV）舒张期充盈情况，对12例左心室流出道梗阻患儿（7例主动脉瓣狭窄和5例主动脉缩窄）以及12名年龄匹配的健康对照者进行了检查。每名儿童均接受了M型超声心动图检查及左心室流入道的脉冲多普勒检查。左心室流出道梗阻患儿接受了心导管检查及球囊血管成形术。他们的超声心动图/多普勒检查在球囊血管成形术前及术后立即在导管室进行。通过M型超声心动图测量左心室腔尺寸、室壁厚度、左心室质量及缩短分数。从多普勒记录中进行以下测量：快速心室充盈时的峰值速度（E峰）及心房收缩时的峰值速度（A峰）、E峰与A峰速度之比、多普勒曲线下的总面积、舒张期前三分之一时间内出现的多普勒总面积百分比（0.33面积分数）、E波下出现的总面积百分比（E面积分数）、A波下出现的总面积百分比（A面积分数）以及E面积与A面积之比。（摘要截断于250字）
