认识、治疗和避免血液疾病：借助数学实现更优医疗？
Understanding, treating and avoiding hematological disease: better medicine through mathematics?
作者信息
Dale David C, Mackey Michael C
机构信息
Department of Medicine, University of Washington, Seattle, WA, 98195, USA,
出版信息
Bull Math Biol. 2015 May;77(5):739-57. doi: 10.1007/s11538-014-9995-x. Epub 2014 Sep 12.
Abstract
This paper traces the experimental, clinical and mathematical modeling efforts to understand a periodic hematological disease-cyclical neutropenia. It is primarily a highly personal account by two scientists from quite different backgrounds of their interactions over almost 40 years and their attempts to understand this intriguing disease. It's also a story of their efforts to offer effective treatments for the patients who suffer from cyclic neutropenia and other conditions causing neutropenia and infections.
摘要
本文追溯了为理解一种周期性血液疾病——周期性中性粒细胞减少症所做的实验、临床及数学建模工作。这主要是两位背景迥异的科学家对他们近40年互动经历的高度个人化记述，以及他们试图理解这种引人入胜的疾病的过程。这也是他们努力为患有周期性中性粒细胞减少症以及其他导致中性粒细胞减少和感染病症的患者提供有效治疗方法的故事。
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