Miller L J
Department of Biology, Gannon University, Erie, PA 16541.
Life Sci. 1989;44(5):355-9. doi: 10.1016/0024-3205(89)90229-4.
Systemic injections of 5-hydroxytryptophan (5-HTP), the precursor to serotonin, stimulates melanin dispersion within dermal melanophores of red-spotted newts (Notophthalmus viridescens). Injections of para-Chlorophenylalanine (PCPA), an inhibitor of serotonin synthesis, inhibited melanin dispersion, and hence darkening of the skin, when newts were transferred to a dark background. The results indicate a role for serotoninergic activity in the background adaptation response in this amphibian.
向红斑蝾螈（绿红东美螈）的真皮黑素细胞内注射血清素的前体5-羟色氨酸（5-HTP），会刺激黑色素扩散。当蝾螈转移到黑暗背景中时，注射血清素合成抑制剂对氯苯丙氨酸（PCPA）会抑制黑色素扩散，从而抑制皮肤变黑。结果表明血清素能活性在这种两栖动物的背景适应反应中发挥作用。
