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性别会影响自闭症谱系障碍的核心缺陷吗?一项关于自闭症谱系障碍女孩和男孩社交沟通与玩耍能力的调查。

Does gender influence core deficits in ASD? An investigation into social-communication and play of girls and boys with ASD.

作者信息

Harrop Clare, Shire Stephanie, Gulsrud Amanda, Chang Ya-Chih, Ishijima Eric, Lawton Kathy, Kasari Connie

机构信息

Center for Autism Research and Treatment, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, 760 Westwood Plaza, Los Angeles, CA, 90095, USA,

出版信息

J Autism Dev Disord. 2015 Mar;45(3):766-77. doi: 10.1007/s10803-014-2234-3.

DOI:10.1007/s10803-014-2234-3
PMID:25217088
Abstract

Due to the predominance of boys diagnosed with autism spectrum disorders (ASD), girls are rarely studied independently. Research specifically focusing on play and social-communication in girls with ASD is extremely varied. We were interested in whether girls with ASD demonstrated equivalent social-communication and play skills in early childhood relative to boys, using two measures focused on the specific quantification of these variables. We also examined whether the associations between developmental variables and social-communication and play differed by gender. Forty girls with ASD were individually matched to 40 boys based on ASD severity. Our results suggest that girls and boys were more similar than different, however they also raise questions about the potential differential associations between development and requesting ability in girls and boys with ASD.

摘要

由于被诊断患有自闭症谱系障碍(ASD)的男孩占主导地位,女孩很少被单独研究。专门针对患有ASD的女孩的游戏和社交沟通的研究极其多样。我们感兴趣的是,患有ASD的女孩在幼儿期相对于男孩是否表现出同等的社交沟通和游戏技能,我们使用了两种专注于对这些变量进行具体量化的测量方法。我们还研究了发育变量与社交沟通和游戏之间的关联是否因性别而异。40名患有ASD的女孩根据ASD严重程度与40名男孩进行了个体匹配。我们的结果表明,女孩和男孩的相似之处多于不同之处,然而,这些结果也引发了关于患有ASD的女孩和男孩在发育与请求能力之间潜在差异关联的问题。

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J Autism Dev Disord. 2014 Mar;44(3):627-35. doi: 10.1007/s10803-013-1913-9.
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Prenatal and postnatal hormone effects on the human brain and cognition.产前和产后激素对人类大脑和认知的影响。
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Short-term trajectories of restricted and repetitive behaviors in minimally verbal children with autism spectrum disorder.自闭症谱系障碍中极轻度语言儿童受限和重复行为的短期轨迹。
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