Markar Sheraz R, Wiggins Tom, Penna Marta, Paraskeva Paraskevas
Academic Surgical Unit, 10th Floor, St Mary's Hospital, Praed Street, London, UK,
J Gastrointest Surg. 2014 Dec;18(12):2214-27. doi: 10.1007/s11605-014-2654-6. Epub 2014 Sep 13.
The aim of this pooled analysis is to determine the effect of single-incision laparoscopic colorectal surgery (SILC) on short-term clinical and oncological outcomes compared with conventional multiport laparoscopic colorectal surgery (CLC).
An electronic search of Embase, Medline, Web of Science, and Cochrane databases was performed. Weighted mean differences (WMD) were calculated for the effect size of SILC on continuous variables and pooled odds ratios (POR) were calculated for discrete variables.
No significant differences between the groups were noted for mortality or morbidity including anastomotic leak, reoperation, pneumonia, wound infection, port-site hernia, and operative time. The benefits of a SILC approach included reduction in time to return of bowel function (WMD = -1.11 days; 95 % C.I. -2.11 to -0.13; P = 0.03), and length of hospital stay (WMD = -1.9 days; 95 % C.I. -2.73 to -1.07; P < 0.0001). Oncological surgical quality was also shown for SILC for the treatment of colorectal cancer with a similar average lymph node harvest, proximal and distal resection margin length compared to CLC.
SILC can be performed safely by experienced laparoscopic surgeons with similar short-term clinical and oncological outcomes to CLC. SILC may further enhance some of the benefits of minimally invasive surgery with a reduction in blood loss and length of hospital stay.
本汇总分析的目的是确定与传统多端口腹腔镜结直肠手术(CLC)相比,单切口腹腔镜结直肠手术(SILC)对短期临床和肿瘤学结局的影响。
对Embase、Medline、Web of Science和Cochrane数据库进行电子检索。计算SILC对连续变量效应大小的加权平均差(WMD),对离散变量计算合并比值比(POR)。
两组在死亡率或发病率方面无显著差异,包括吻合口漏、再次手术、肺炎、伤口感染、切口疝和手术时间。SILC方法的益处包括肠道功能恢复时间缩短(WMD = -1.11天;95%置信区间-2.11至-0.13;P = 0.03)和住院时间缩短(WMD = -1.9天;95%置信区间-2.73至-1.07;P < 0.0001)。SILC治疗结直肠癌的肿瘤手术质量也得到了体现,与CLC相比,平均淋巴结清扫数量、近端和远端切缘长度相似。
经验丰富的腹腔镜外科医生可以安全地进行SILC,其短期临床和肿瘤学结局与CLC相似。SILC可能会进一步增强微创手术的一些益处,减少失血和缩短住院时间。