Suppr超能文献

来自玻利维亚北永加斯省非洲裔玻利维亚人的15个常染色体STR标记的群体数据。

Population data of 15 autosomal STR markers from Afro-Bolivians of Nor Yungas Province (Bolivia).

作者信息

Parolin María Laura, Iudica Celia Estela, Lancelotti Julio Lucio, Sambuco Lorena Andrea, Jaureguiberry Stella Maris, Avena Sergio Alejandro, Carnese Francisco Raúl

机构信息

Sistemática y Evolución, Laboratorio de Biología Molecular, Centro Nacional Patagónico-CONICET, Unidad de Diversidad, Bvd. Brown 2915, Puerto Madryn, Chubut, Argentina,

出版信息

Int J Legal Med. 2015 May;129(3):463-4. doi: 10.1007/s00414-014-1080-3. Epub 2014 Sep 9.

Abstract

Allele frequencies and forensic parameters for 15 autosomal loci included in the AmpFlSTR® Identifiler kit were estimated in a sample of 57 unrelated Afro-descendants from Nor Yungas (Bolivia). Buccal swabs samples were obtained from voluntary donors, after consent was given. All loci were in Hardy-Weinberg equilibrium after Bonferroni correction. D21S11 was the most informative locus, while the least discriminating locus was D3S1358. The combined power of discrimination and the combined probability of exclusion were >0.99999999 and >0.99997, respectively. The multidimensional scaling (MDS) plot generated by Rst matrix supported that Afro-Bolivians of Nor Yungas preserved a stronger African descent compared to other admixed Latin American populations. These results amplified the Bolivian databases of autosomal STR loci and may provide a useful tool for human identification tests and population genetic studies.

摘要

在来自玻利维亚永加斯地区的57名无亲缘关系的非洲裔后裔样本中,对包含在AmpFlSTR® Identifiler试剂盒中的15个常染色体基因座的等位基因频率和法医参数进行了估计。在获得同意后,从自愿捐赠者处采集口腔拭子样本。经过Bonferroni校正后,所有基因座均处于哈迪-温伯格平衡状态。D21S11是信息量最大的基因座,而鉴别力最小的基因座是D3S1358。联合鉴别力和联合排除概率分别>0.99999999和>0.99997。由Rst矩阵生成的多维标度(MDS)图表明,与其他混合的拉丁美洲人群相比,永加斯地区的玻利维亚非洲裔保留了更强的非洲血统。这些结果扩充了玻利维亚常染色体STR基因座数据库,并可能为人类身份鉴定测试和群体遗传学研究提供有用的工具。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验