Arlequin（版本 3.0）：一个用于群体遗传学数据分析的集成软件包。
Arlequin (version 3.0): an integrated software package for population genetics data analysis.
机构信息
Computational and Molecular Population Genetics Lab, Zoological Institute, University of Berne, Baltzerstrasse 6, 3012 Berne, Switzerland.
出版信息
Evol Bioinform Online. 2007 Feb 23;1:47-50.
Abstract
Arlequin ver 3.0 is a software package integrating several basic and advanced methods for population genetics data analysis, like the computation of standard genetic diversity indices, the estimation of allele and haplotype frequencies, tests of departure from linkage equilibrium, departure from selective neutrality and demographic equilibrium, estimation or parameters from past population expansions, and thorough analyses of population subdivision under the AMOVA framework. Arlequin 3 introduces a completely new graphical interface written in C++, a more robust semantic analysis of input files, and two new methods: a Bayesian estimation of gametic phase from multi-locus genotypes, and an estimation of the parameters of an instantaneous spatial expansion from DNA sequence polymorphism. Arlequin can handle several data types like DNA sequences, microsatellite data, or standard multi-locus genotypes. A Windows version of the software is freely available on http://cmpg.unibe.ch/software/arlequin3.
摘要
Arlequin ver 3.0 是一个软件包，集成了几种用于群体遗传学数据分析的基本和高级方法，例如计算标准遗传多样性指数、估计等位基因和单倍型频率、检验连锁不平衡、偏离选择中性和种群平衡的偏离、从过去种群扩张中估计参数，以及在 AMOVA 框架下对种群细分进行全面分析。Arlequin 3 引入了一个完全用 C++编写的全新图形界面，对输入文件进行更强大的语义分析，以及两种新方法：从多基因座基因型中贝叶斯估计配子相，以及从 DNA 序列多态性估计瞬时空间扩张的参数。Arlequin 可以处理多种数据类型，如 DNA 序列、微卫星数据或标准多基因座基因型。该软件的 Windows 版本可在 http://cmpg.unibe.ch/software/arlequin3 上免费获得。
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