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左心室肥厚作为心律失常和猝死的一个因素。

Left ventricular hypertrophy as a factor in arrhythmias and sudden death.

作者信息

McLenachan J M, Dargie H J

机构信息

Department of Cardiology, Western Infirmary, Glasgow, United Kingdom.

出版信息

Am J Hypertens. 1989 Feb;2(2 Pt 1):128-31. doi: 10.1093/ajh/2.2.128.

DOI:10.1093/ajh/2.2.128
PMID:2521792
Abstract

Hypertensive patients with left ventricular hypertrophy (LVH) are predisposed to sudden cardiac death. Several studies have demonstrated that complex ventricular arrhythmias, including episodes of nonsustained ventricular tachycardia, occur commonly during ambulatory electrocardiographic monitoring of hypertensive patients with LVH. The prognostic significance of such arrhythmias is not known. In other forms of cardiac hypertrophy, however, such as hypertrophic cardiomyopathy, complex ventricular arrhythmias detected during ambulatory monitoring are predictive of subsequent sudden death and there is some evidence that appropriate antiarrhythmic drug therapy may reduce mortality.

摘要

患有左心室肥厚(LVH)的高血压患者易发生心源性猝死。多项研究表明,包括非持续性室性心动过速发作在内的复杂性室性心律失常,在对患有LVH的高血压患者进行动态心电图监测期间很常见。此类心律失常的预后意义尚不清楚。然而,在其他形式的心脏肥厚中,如肥厚型心肌病,动态监测期间检测到的复杂性室性心律失常可预测随后的猝死,并且有一些证据表明适当的抗心律失常药物治疗可能会降低死亡率。

相似文献

1
Left ventricular hypertrophy as a factor in arrhythmias and sudden death.左心室肥厚作为心律失常和猝死的一个因素。
Am J Hypertens. 1989 Feb;2(2 Pt 1):128-31. doi: 10.1093/ajh/2.2.128.
2
Significance of ventricular arrhythmias in systemic hypertension with left ventricular hypertrophy.室性心律失常在伴有左心室肥厚的系统性高血压中的意义。
Am J Cardiol. 1992 Apr 1;69(9):913-7. doi: 10.1016/0002-9149(92)90792-w.
3
Ventricular arrhythmias in hypertensive left ventricular hypertrophy. Relationship to coronary artery disease, left ventricular dysfunction, and myocardial fibrosis.高血压性左心室肥厚中的室性心律失常。与冠状动脉疾病、左心室功能障碍及心肌纤维化的关系。
Am J Hypertens. 1990 Oct;3(10):735-40. doi: 10.1093/ajh/3.10.735.
4
Ventricular arrhythmias in patients with hypertensive left ventricular hypertrophy.
N Engl J Med. 1987 Sep 24;317(13):787-92. doi: 10.1056/NEJM198709243171302.
5
Hypertensive concentric left ventricular hypertrophy: when is ventricular ectopic activity increased?高血压性同心性左心室肥厚:室性异位活动何时会增加?
South Med J. 1988 Jun;81(6):696-700. doi: 10.1097/00007611-198806000-00004.
6
[Arrhythmias in hypertrophic cardiomyopathy. Significance and therapeutic consequences].[肥厚型心肌病中的心律失常。意义及治疗后果]
Herz. 1985 Apr;10(2):91-101.
7
Noninvasive diagnosis of ventricular arrhythmias by means of ambulatory-ECG monitoring.通过动态心电图监测对室性心律失常进行无创诊断。
Herz. 1990 Feb;15(1):1-10.
8
Hypertension and sudden death. Increased ventricular ectopic activity in left ventricular hypertrophy.高血压与猝死。左心室肥厚时室性异位活动增加。
Am J Med. 1984 Jul;77(1):18-22. doi: 10.1016/0002-9343(84)90430-3.
9
[Arrhythmia and anti-arrhythmia therapy as prognostic risks].
Herz. 1991 Sep;16 Spec No 1:314-7, 323.
10
[Concentric left ventricular hypertrophy in patients with hypertension. When should ventricular hyperexcitability be searched for?].
Arch Mal Coeur Vaiss. 1990 Jul;83(8):1107-10.

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Cardiac Magnetic Resonance and Ventricular Arrhythmia Risk Assessment in Chronic Ischemic Cardiomyopathy: An Unmet Need?慢性缺血性心肌病中心脏磁共振成像与室性心律失常风险评估:一项未满足的需求?
Rev Cardiovasc Med. 2022 Jun 28;23(7):246. doi: 10.31083/j.rcm2307246. eCollection 2022 Jul.
2
Sudden cardiac death: epidemiology and risk factors.心脏性猝死:流行病学和危险因素。
Nat Rev Cardiol. 2010 Apr;7(4):216-25. doi: 10.1038/nrcardio.2010.3. Epub 2010 Feb 9.
3
Gap junction remodeling and spironolactone-dependent reverse remodeling in the hypertrophied heart.
肥厚心肌中的缝隙连接重塑与螺内酯依赖性逆向重塑
Circ Res. 2009 Feb 13;104(3):365-71. doi: 10.1161/CIRCRESAHA.108.184044. Epub 2008 Dec 18.
4
Cardiac arrhythmias as correlated with the circadian rhythm of arterial pressure in hypertensive subjects with and without left ventricular hypertrophy.有或无左心室肥厚的高血压患者的心律失常与动脉压昼夜节律的相关性
Eur J Clin Pharmacol. 1990;39 Suppl 1:S49-51.