Jabbarvand Mahmoud, Hashemian Hesam, Khodaparast Mehdi, Ghadimi Hadi, Khalilipour Elias
From the Department of Ophthalmology, Ophthalmology Research Center, Tehran University of Medical Sciences, Farabi Eye Hospital, Tehran, Iran.
From the Department of Ophthalmology, Ophthalmology Research Center, Tehran University of Medical Sciences, Farabi Eye Hospital, Tehran, Iran.
J Cataract Refract Surg. 2014 Nov;40(11):1805-12. doi: 10.1016/j.jcrs.2014.02.044. Epub 2014 Sep 11.
To evaluate the visual and refractive outcomes, endothelial cell count (ECC), ocular surface changes, corneal aberrations, and biomechanical profile changes after femtosecond laser-assisted anterior lamellar keratoplasty surgery for superficial corneal scars.
Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Prospective case series.
Patients with superficial corneal scars had femtosecond laser-assisted anterior lamellar keratoplasty. Visual and refractive results, ECC, ocular surface changes, corneal aberrations, and biomechanical profiles were assessed preoperatively and for 1 year postoperatively.
Nineteen eyes (19 patients) were evaluated. A significant decline occurred in refractive astigmatism and corneal astigmatism after 1 year. There was a nonsignificant reduction in corneal hysteresis and the corneal resistance factor from preoperatively to 1 year postoperatively. The corneal-compensated intraocular pressure (IOP) and Goldmann-correlated IOP increased during the follow-up; the increase was not significant. A statistically insignificant reduction in the root mean square for trefoil and spherical aberrations occurred between 1 month and 1 year postoperatively (P=.1 and P=.4, respectively). The decreases in primary coma and total higher-order aberrations approached significance (P=.08 and P=.07, respectively). There were no significant changes in the central corneal thickness, ECC, or ocular surface parameters. No intraoperative complications occurred.
Femtosecond laser-assisted anterior lamellar keratoplasty was an efficient and safe procedure for improving the quality of vision in patients with anterior corneal pathology, and the results remained stable during the 1-year follow-up.
No author has a financial or proprietary interest in any material or method mentioned.
评估飞秒激光辅助前板层角膜移植术治疗浅层角膜瘢痕后的视觉和屈光效果、内皮细胞计数（ECC）、眼表变化、角膜像差和生物力学特征变化。
伊朗德黑兰医科大学法拉比眼科医院。
前瞻性病例系列。
浅层角膜瘢痕患者接受飞秒激光辅助前板层角膜移植术。术前及术后1年评估视觉和屈光结果、ECC、眼表变化、角膜像差和生物力学特征。
评估了19只眼（19例患者）。1年后屈光性散光和角膜散光显著下降。从术前到术后1年，角膜滞后和角膜阻力因子有不显著的降低。随访期间角膜补偿眼压（IOP）和Goldmann相关眼压升高；升高不显著。术后1个月至1年，三叶形像差和球差的均方根有统计学上不显著的降低（分别为P = 0.1和P = 0.4）。初级彗差和总高阶像差的降低接近显著水平（分别为P = 0.08和P = 0.07）。中央角膜厚度、ECC或眼表参数无显著变化。未发生术中并发症。
飞秒激光辅助前板层角膜移植术是改善眼前段角膜病变患者视力质量的一种有效且安全的手术方法，在1年随访期间结果保持稳定。
没有作者对文中提及的任何材料或方法有财务或专利权益。
