Schubert Matthew M, Grant Gary, Horner Katy, King Neil, Leveritt Michael, Sabapathy Surendran, Desbrow Ben
School of Allied Health Sciences, Griffith Health Institute, Griffith University, Gold Coast, Qld., Australia.
School of Pharmacy, Griffith University, Gold Coast, Qld., Australia.
Appetite. 2014 Dec;83:317-326. doi: 10.1016/j.appet.2014.09.006. Epub 2014 Sep 16.
Coffee is one of the most widely consumed beverages in the world and has a number of potential health benefits. Coffee may influence energy expenditure and energy intake, which in turn may affect body weight. However, the influence of coffee and its constituents - particularly caffeine - on appetite remains largely unexplored. The objective of this study was to examine the impact of coffee consumption (with and without caffeine) on appetite sensations, energy intake, gastric emptying, and plasma glucose between breakfast and lunch meals. In a double-blind, randomised crossover design. Participants (n = 12, 9 women; Mean ± SD age and BMI: 26.3 ± 6.3 y and 22.7 ± 2.2 kg•m⁻²) completed 4 trials: placebo (PLA), decaffeinated coffee (DECAF), caffeine (CAF), and caffeine with decaffeinated coffee (COF). Participants were given a standardised breakfast labelled with ¹³C-octanoic acid and 225 mL of treatment beverage and a capsule containing either caffeine or placebo. Two hours later, another 225 mL of the treatment beverage and capsule was administered. Four and a half hours after breakfast, participants were given access to an ad libitum meal for determination of energy intake. Between meals, participants provided exhaled breath samples for determination of gastric emptying; venous blood and appetite sensations. Energy intake was not significantly different between the trials (Means ± SD, p> 0.05; Placebo: 2118 ± 663 kJ; Decaf: 2128 ± 739 kJ; Caffeine: 2287 ± 649 kJ; Coffee: 2016 ± 750 kJ); Other than main effects of time (p <0.05), no significant differences were detected for appetite sensations or plasma glucose between treatments (p > 0.05). Gastric emptying was not significantly different across trials (p > 0.05). No significant effects of decaffeinated coffee, caffeine or their combination were detected. However, the consumption of caffeine and/or coffee for regulation of energy balance over longer periods of time warrant further investigation.
咖啡是世界上消费最为广泛的饮品之一,具有许多潜在的健康益处。咖啡可能会影响能量消耗和能量摄入,进而可能影响体重。然而,咖啡及其成分——尤其是咖啡因——对食欲的影响在很大程度上仍未得到充分研究。本研究的目的是检验早餐和午餐之间饮用咖啡(含咖啡因和不含咖啡因)对食欲感觉、能量摄入、胃排空和血浆葡萄糖的影响。采用双盲、随机交叉设计。参与者(n = 12,9名女性;平均±标准差年龄和体重指数:26.3±6.3岁和22.7±2.2 kg•m⁻²)完成了4项试验:安慰剂(PLA)、脱咖啡因咖啡(DECAF)、咖啡因(CAF)以及含咖啡因的脱咖啡因咖啡(COF)。给参与者提供一份标有¹³C - 辛酸的标准化早餐、225毫升治疗饮品以及一粒含有咖啡因或安慰剂的胶囊。两小时后,再给予225毫升治疗饮品和胶囊。早餐后4个半小时,让参与者随意进食以测定能量摄入。两餐之间,参与者提供呼出的气体样本以测定胃排空情况;采集静脉血并记录食欲感觉。各试验之间的能量摄入无显著差异(平均值±标准差,p>0.05;安慰剂:2118±663千焦;脱咖啡因咖啡:2128±739千焦;咖啡因:2287±649千焦;咖啡:2016±750千焦);除了时间的主要影响(p<0.05)外,各治疗组之间的食欲感觉或血浆葡萄糖未检测到显著差异(p>0.05)。各试验之间的胃排空无显著差异(p>0.