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先天性脊柱侧凸合并脊髓纵裂畸形的一期手术治疗

[One stage surgical treatment of congenital scoliosis associated with split cord malformation].

作者信息

Shen Chao, Tao Huiren, Hui Hua, Jiang Xiaofan, Chen Bo, Huang Jinghui, Yang Weizhou, Li Tao, Luo Zhuojing

机构信息

Department of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.

Department of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. Email:

出版信息

Zhonghua Wai Ke Za Zhi. 2014 Jun;52(6):431-5.

Abstract

OBJECTIVE

To investigate the clinical results of one stage surgical treatment in congenital scoliosis (CS) patients associated with split cord malformation (SCM).

METHODS

Between January 2007 and December 2010, 50 patients underwent one stage surgical treatment for CS associated with SCM. Among of them, 38 patients (13 male and 25 female) with an average age of (15 ± 6) years, who were followed up in the clinic at least 2 years longer, were include in the study. There were 12 patients with Type I SCM and 26 patients with Type II SCM Pre-operative, post-operative and the follow-up imaging data were collected and compared by paired t-test, while imaging data between Type I SCM group and Type II SCM group were compared by group t-test. Bony spur was first resected to the Type I SCM while nothing was done to the Type II SCM. Then, all patients were followed by posterior corrective procedure in one stage. Meanwhile, duraplasty were only applied in 5 patients whose dural cleft were more than 1 cm longer.

RESULTS

The average follow-up was 41 ± 13 months (range, 26-68 months). The average operation time was 491 ± 152 minutes (range, 105-780 minutes) and the average blood loss was (1 933 ± 1 516) ml (range, 1 000-8 000 ml). The mean major coronal curve was corrected from 70° ± 26° preoperatively to 312° ± 16° postoperatively with a correction rate of 57% ± 18%, and 33° ± 17° at the final follow-up with a correction rate of 54% ± 20%. The mean major sagittal curve was corrected from 43° ± 31° to 26° ± 16°, and 27° ± 15° at the final follow-up. The postoperative complication occurred in 2 patients (5.3%) with Type I SCM, including neurological deterioration in 1 patient (2.6%) and cerebrospinal fluid leakage in 1 patient (2.6%). There were no paralysis and other serious complications. The patients who suffered from neurological deterioration recovered to the preoperative neurological status at 30 months postoperatively and no further improvement at the final follow-up.

CONCLUSION

It is safe and efficient to treat the CS associated with SCM by one stage surgery without increasing the risk of neurological complications postoperatively.

摘要

目的

探讨一期手术治疗合并脊髓纵裂畸形(SCM)的先天性脊柱侧凸(CS)患者的临床疗效。

方法

2007年1月至2010年12月,50例合并SCM的CS患者接受了一期手术治疗。其中38例患者(男13例,女25例)平均年龄(15±6)岁,在门诊至少随访2年以上,纳入本研究。I型SCM患者12例,II型SCM患者26例。收集术前、术后及随访的影像学资料,采用配对t检验进行比较,I型SCM组与II型SCM组影像学资料采用成组t检验进行比较。对于I型SCM,首先切除骨赘,而II型SCM则不做处理。然后,所有患者均接受一期后路矫正手术。同时,仅对5例硬脊膜裂孔超过1cm的患者进行了硬脊膜成形术。

结果

平均随访时间为41±13个月(范围26 - 68个月)。平均手术时间为491±152分钟(范围105 - 780分钟),平均失血量为(1933±1516)ml(范围1000 - 8000ml)。主要冠状面弯曲度术前平均为70°±26°,术后为31°±16°,矫正率为57%±18%,末次随访时为33°±17°,矫正率为54%±20%。主要矢状面弯曲度术前平均为43°±31°,术后为26°±16°,末次随访时为27°±15°。I型SCM患者术后并发症发生2例(5.3%),其中神经功能恶化1例(2.6%),脑脊液漏1例(2.6%)。无瘫痪及其他严重并发症。神经功能恶化患者术后30个月恢复至术前神经状态,末次随访时无进一步改善。

结论

一期手术治疗合并SCM的CS安全有效,且不增加术后神经并发症风险。

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