Rocca Walter A, Boyd Cynthia M, Grossardt Brandon R, Bobo William V, Finney Rutten Lila J, Roger Véronique L, Ebbert Jon O, Therneau Terry M, Yawn Barbara P, St Sauver Jennifer L
Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN; Department of Neurology, College of Medicine, Mayo Clinic, Rochester, MN.
Division of Geriatric Medicine and Gerontology, School of Medicine, Johns Hopkins University, Baltimore, MD.
Mayo Clin Proc. 2014 Oct;89(10):1336-49. doi: 10.1016/j.mayocp.2014.07.010. Epub 2014 Sep 11.
To describe the prevalence of multimorbidity involving 20 selected chronic conditions in a geographically defined US population, emphasizing age, sex, and racial/ethnic differences.
Using the Rochester Epidemiology Project records linkage system, we identified all residents of Olmsted County, Minnesota, on April 1, 2010, and electronically extracted the International Classification of Diseases, Ninth Revision codes associated with all health care visits made between April 1, 2005, and March 31, 2010 (5-year capture frame). Using these codes, we defined the 20 common chronic conditions recommended by the US Department of Health and Human Services. We counted only persons who received at least 2 codes for a given condition separated by more than 30 days, and we calculated the age-, sex-, and race/ethnicity-specific prevalence of multimorbidity.
Of the 138,858 study participants, 52.4% were women (n=72,732) and 38.9% had 1 or more conditions (n=54,012), 22.6% had 2 or more conditions (n=31,444), and 4.9% had 5 or more conditions (n=6853). The prevalence of multimorbidity (≥2 conditions) increased steeply with older age and reached 77.3% at 65 years and older. However, the absolute number of people affected by multimorbidity was higher in those younger than 65 years. Although the prevalence of multimorbidity was similar in men and women overall, the most common dyads and triads of conditions varied by sex. Compared with white persons, the prevalence of multimorbidity was slightly higher in black persons and slightly lower in Asian persons.
Multimorbidity is common in the general population; it increases steeply with older age, has different patterns in men and women, and varies by race/ethnicity.
描述美国一个地理区域特定人群中涉及20种选定慢性病的共病患病率，重点关注年龄、性别和种族/民族差异。
利用罗切斯特流行病学项目记录链接系统，我们确定了2010年4月1日明尼苏达州奥尔姆斯特德县的所有居民，并以电子方式提取了2005年4月1日至2010年3月31日（5年捕获期）期间所有医疗就诊相关的国际疾病分类第九版编码。利用这些编码，我们定义了美国卫生与公众服务部推荐的20种常见慢性病。我们仅统计在给定疾病上至少获得2个间隔超过30天编码的人，并计算共病的年龄、性别和种族/民族特异性患病率。
在138,858名研究参与者中，52.4%为女性（n = 72,732），38.9%患有1种或更多疾病（n = 54,012），22.6%患有2种或更多疾病（n = 31,444），4.9%患有5种或更多疾病（n = 6853）。共病（≥2种疾病）的患病率随年龄增长急剧上升，在65岁及以上人群中达到77.3%。然而，受共病影响的绝对人数在65岁以下人群中更高。尽管总体上男性和女性的共病患病率相似，但最常见的两种和三种疾病组合因性别而异。与白人相比，黑人的共病患病率略高，亚洲人的共病患病率略低。
共病在普通人群中很常见；它随年龄增长急剧上升，在男性和女性中模式不同，且因种族/民族而异。
