Gavalas M, Meisner R, Labropoulos N, Gasparis A, Tassiopoulos A
Department of Vascular Surgery, Stony Brook University Medical Center, Stony Brook, NY, USA
Department of Vascular Surgery, Stony Brook University Medical Center, Stony Brook, NY, USA.
Vasc Endovascular Surg. 2014 Oct-Nov;48(7-8):445-51. doi: 10.1177/1538574414551206. Epub 2014 Sep 15.
Fibromuscular dysplasia (FMD) is a nonatherosclerotic, noninflammatory vascular disease that most commonly affects the renal and extracranial carotid arteries. We present 3 cases of renal infarction complicating renal artery FMD in 42-, 43-, and 46-year-old females and provide a comprehensive review of the literature on this topic. In our patients, oral anticoagulation therapy was used to treat all cases of infarction, and percutaneous angioplasty was used nonemergently in one case to treat refractory hypertension. All patients remained stable at 1-year follow-up. This is consistent with outcomes in previously published reports where conservative medical management was comparable to surgical and interventional therapies. Demographic differences may also exist in patients with renal infarction and FMD. A higher prevalence of males and a younger age at presentation have been found in these patients when compared to the general population with FMD.
纤维肌性发育异常（FMD）是一种非动脉粥样硬化、非炎症性血管疾病，最常累及肾动脉和颅外颈动脉。我们报告了3例分别为42岁、43岁和46岁女性的肾梗死合并肾动脉FMD病例，并对该主题的文献进行了全面综述。在我们的患者中，口服抗凝治疗用于治疗所有梗死病例，1例患者非急诊行经皮血管成形术以治疗难治性高血压。所有患者在1年随访时均保持稳定。这与先前发表的报告结果一致，在这些报告中，保守药物治疗与手术及介入治疗效果相当。肾梗死合并FMD的患者可能也存在人口统计学差异。与一般FMD患者相比，这些患者中男性患病率更高且发病年龄更年轻。
