Huang Shih-Han S, Shah Sachin, Thomson Benjamin K A, Laporte Sally, Filler Guido, Lindsay Robert M
Western University and London Health Sciences Centre, Department of Medicine, Nephrology Division, London, Ont., Canada.
Blood Purif. 2014;38(1):13-7. doi: 10.1159/000363049. Epub 2014 Sep 13.
It is important to know the relative clearances obtained when using single-needle versus double-needle cannulation techniques.
Twelve hemodialysis treatments were conducted using a machine that is capable of single-needle as well as double-needle cannulation. Single-needle and double-needle blood flow rates, as well as urea clearance, were compared.
The measured blood flow rates were 368 ± 11 ml/min, 294 ± 4 ml/min, 200 ± 0 ml/min, and 100 ± 0 ml/min during double-needle hemodialysis and were 201 ± 10.9 ml/min, 173 ± 44.9 ml/min, 103 ± 4.1 ml/min, and 45 ± 4.9 ml/min during single-needle hemodialysis. The hemodialysis urea clearances at similar blood flow rate (approximately 200 ml/min) were 167 ± 4 ml/min and 161 ± 9 ml/min (paired t test; p > 0.05), respectively.
The measured blood flow rates and urea clearances during single-needle hemodialysis were approximately half of the measured blood flow rate during double-needle hemodialysis, and should be used in selected settings.
了解使用单针与双针插管技术时获得的相对清除率很重要。
使用一台能够进行单针和双针插管的机器进行了12次血液透析治疗。比较了单针和双针的血流速率以及尿素清除率。
在双针血液透析期间测得的血流速率分别为368±11毫升/分钟、294±4毫升/分钟、200±0毫升/分钟和100±0毫升/分钟，在单针血液透析期间分别为201±10.9毫升/分钟、173±44.9毫升/分钟、103±4.1毫升/分钟和45±4.9毫升/分钟。在相似血流速率（约200毫升/分钟）下的血液透析尿素清除率分别为167±4毫升/分钟和161±9毫升/分钟（配对t检验；p>0.05）。
单针血液透析期间测得的血流速率和尿素清除率约为双针血液透析期间测得血流速率的一半，应在特定情况下使用。
