Boin Dahiana Pulgar, Baez Jaime Jans, Guajardo Militza Petric, Benavides David Oddo, Ortega Maria Elena Navarro, Valdés Dravna Razmilic, Apphun Mauricio Camus
Department of Oncology and Maxillofacial Surgery, College of Medicine, Pontifical Catholic University of Chile, Marcoleta 352, Santiago 8330033, Chile.
Department of Pathologic Anatomy, College of Medicine, Pontifical Catholic University of Chile, Marcoleta 352, Santiago 8330033, Chile.
Ecancermedicalscience. 2014 Sep 2;8:461. doi: 10.3332/ecancer.2014.461. eCollection 2014.
Papillary breast lesions are rare and constitute less than 10% of benign breast lesions and less than 1% of breast carcinomas.
To analyse the clinical presentation, preoperative evaluation, and surgical and anatomopathological characteristics of the patients operated on for papillary breast lesions.
Retrospective descriptive and analytical study. We analysed the database of patients with definitive histopathological diagnosis of papillary breast lesions operated on at our institution from January 2004 to May 2013.
During the period described, 70 patients with histopathological diagnosis of papillary breast lesions were operated upon. The median age was 50 years (19-86 years). Thirty-seven patients (52.8%) were symptomatic at diagnosis. Preoperative ultrasound was reported to be altered in all patients. A mammography showed pathologic findings in only 50% of cases. All patients underwent partial mastectomy, after needle localisation under ultrasound, if the lesion was not palpable on physical examination. The final pathological diagnosis was: benign papillary lesion in 55 patients (78.6%) and malignant in 15 patients (21.4%). Adjuvant treatment was performed in all malignant cases. Median follow-up was 46 months (3-115 months).
Patients with papillary breast lesions presented with symptoms in half of all cases. There was a high frequency of malignancy (21.4%), therefore surgical resection was recommended for papillary breast lesions.
乳腺乳头状病变较为罕见，在良性乳腺病变中占比不到10%，在乳腺癌中占比不到1%。
分析接受乳腺乳头状病变手术患者的临床表现、术前评估以及手术和解剖病理学特征。
回顾性描述性和分析性研究。我们分析了2004年1月至2013年5月在我院接受手术且有明确组织病理学诊断为乳腺乳头状病变患者的数据库。
在所述期间，70例组织病理学诊断为乳腺乳头状病变的患者接受了手术。中位年龄为50岁（19 - 86岁）。37例患者（52.8%）在诊断时有症状。据报告所有患者术前超声均有改变。乳房X线摄影仅在50%的病例中显示出病理结果。如果病变在体格检查中不可触及，所有患者在超声引导下针定位后均接受了保乳手术。最终病理诊断为：55例患者（78.6%）为良性乳头状病变，15例患者（21.4%）为恶性。所有恶性病例均接受了辅助治疗。中位随访时间为46个月（3 - 115个月）。
乳腺乳头状病变患者半数有症状。恶性率较高（21.4%），因此建议对乳腺乳头状病变进行手术切除。
