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用于肿瘤切除后心脏结构重建的细胞外基质。

Extracellular matrix for reconstruction of cardiac structures after tumour resections.

作者信息

Sündermann Simon H, Müggler Oliver, Caliskan Etem, Reser Diana, Manka Robert, Holubec Tomas, Czerny Martin, Falk Volkmar

机构信息

Division of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland

Division of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland.

出版信息

Interact Cardiovasc Thorac Surg. 2015 Jan;20(1):10-4. doi: 10.1093/icvts/ivu310. Epub 2014 Sep 17.

Abstract

OBJECTIVES

To describe the use of a new extracellular matrix patch as a means for atrial reconstruction in patients with cardiac tumours.

METHODS

A new extracellular matrix patch was used to reconstruct atrial and neighbouring structures after tumour resections. In 1 case, it was used to reconstruct the atrial septum and the left atrial roof after excision of a huge myxoma. In a second case, it was used to reconstruct the right atrium, including the superior vena cava after excision of a primary cardiac sarcoma. In a third case, it was used to reconstruct both atria, the right-sided pulmonary venous confluence and the roof of the coronary sinus after excision of a metastasis of malignant melanoma.

RESULTS

In all cases, reconstruction was successful and facilitated because of the flexible and thin character of the extracellular matrix, which also seemed to be advantageous with regards to haemostasis.

CONCLUSIONS

Extracellular matrix patches are a potential alternative for pericardial patches for complex reconstructions of atrial structures because of their pliable characteristics and consecutively reduced need for haemostatic stitches.

摘要

目的

描述一种新型细胞外基质补片在心脏肿瘤患者心房重建中的应用。

方法

使用新型细胞外基质补片在肿瘤切除后重建心房及相邻结构。1例中,在巨大黏液瘤切除后用于重建房间隔和左心房顶部。第2例中,在原发性心脏肉瘤切除后用于重建右心房,包括上腔静脉。第3例中,在恶性黑色素瘤转移灶切除后用于重建双侧心房、右侧肺静脉汇合处和冠状窦顶部。

结果

在所有病例中,重建均获成功且因细胞外基质柔软轻薄的特性而更为便利,这在止血方面似乎也具有优势。

结论

由于细胞外基质补片具有柔韧性且减少了止血缝线的需求,因此对于心房结构的复杂重建而言,它是心包补片的一种潜在替代物。

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