从甜菊糖苷A生物转化为甜菊糖苷D的反应中分离并鉴定甜菊糖苷D2的结构

Isolation and structure elucidation of rebaudioside D2 from bioconversion reaction of rebaudioside A to rebaudioside D.

作者信息

Prakash Indra, Bunders Cynthia, Devkota Krishna P, Charan Romila D, Ramirez Catherine, Parikh Maunik, Markosyan Avetik

出版信息

Nat Prod Commun. 2014 Aug;9(8):1135-8.

Abstract

We report the isolation and complete structure of an isomer of rebaudioside D, known as rebaudioside D2. This novel steviol glycoside was isolated from a bioconversion reaction of rebaudioside A to rebaudioside D. Rebaudioside D2 possesses a relatively rare 1 --> 6 sugar linkage, which was discovered by extensive analysis of NMR (1H, 13C, COSY, HSQC-DEPT, HMBC, 1D TOCSY and NOESY) and mass spectral data.

摘要

我们报道了一种莱鲍迪苷D的异构体——莱鲍迪苷D2的分离及完整结构。这种新型甜菊醇糖苷是从莱鲍迪苷A向莱鲍迪苷D的生物转化反应中分离得到的。莱鲍迪苷D2具有一种相对罕见的1→6糖键，这是通过对核磁共振（1H、13C、COSY、HSQC - DEPT、HMBC、1D TOCSY和NOESY）和质谱数据进行广泛分析发现的。