Lobstein D D, Ismail A H
Department of Health Promotion, University of New Mexico, Albuquerque 87131.
Med Sci Sports Exerc. 1989 Apr;21(2):161-6.
The purpose of the present study was to investigate changes in the resting plasma beta-endorphin/-lipotropin (beta E/beta-LPH) concentration that may occur with exercise training. A treatment group (N = 10) of previously sedentary, psychologically normal, and medically healthy middle-aged men trained for 4 months in a structured fitness program. The treatment group was compared with two age-matched groups: a jogger group (N = 10) and a sedentary group (N = 10). Venous blood was collected in the early morning after the subjects had been fasting for at least 12 h. The subjects were also resting at the time of blood collection. Resting plasma beta E/beta-LPH (measured by radioimmunoassay) decreased (P less than 0.05) following the 4 months of exercise training in the treatment group, from 11.01 +/- 1.62 (SE) to 7.22 +/- 0.99 pmol.1-1. The jogger and sedentary groups demonstrated no changes in the resting plasma beta E/beta-LPH concentration following the 4 months. Aerobic fitness, measured by the maximal oxygen uptake (VO2max), increased (P less than 0.01) from 36.56 +/- 2.58 (SE) to 44.85 +/- 1.34 ml.kg-1.min-1 in the treatment group after the 4 months of training. There were no changes in VO2max for either the jogger group or the sedentary group following the 4 months. In conclusion, beta E/beta-LPH in the plasma of resting middle-aged men appeared to be decreased after 4 months of aerobic training.
本研究的目的是调查运动训练可能导致的静息血浆β-内啡肽/β-促脂解素（βE/β-LPH）浓度变化。一组治疗组（N = 10）为先前久坐不动、心理正常且身体健康的中年男性，他们参加了一项为期4个月的结构化健身计划训练。将治疗组与两个年龄匹配组进行比较：一个慢跑组（N = 10）和一个久坐组（N = 10）。在受试者至少禁食12小时后的清晨采集静脉血。采血时受试者也处于静息状态。治疗组经过4个月的运动训练后，静息血浆βE/β-LPH（通过放射免疫测定法测量）从11.01±1.62（标准误）降至7.22±0.99 pmol·1⁻¹，降低了（P＜0.05）。4个月后，慢跑组和久坐组的静息血浆βE/β-LPH浓度没有变化。通过最大摄氧量（VO₂max）测量的有氧适能在治疗组经过4个月训练后从36.56±2.58（标准误）增加到44.85±1.34 ml·kg⁻¹·min⁻¹（P＜0.01）。4个月后，慢跑组和久坐组的VO₂max均无变化。总之，经过4个月的有氧训练后，静息中年男性血浆中的βE/β-LPH似乎降低了。
