Freemasons Foundation Centre for Men׳s Health, Discipline of Medicine, School of Medicine, The University of Adelaide, SA 5005, Australia; Department of Rehabilitation Psychology and Psychotherapy, Institute of Psychology, University of Freiburg, Germany; Heart Failure Support Service, The Queen Elizabeth Hospital, Woodville, SA, Australia.
Heart Failure Support Service, The Queen Elizabeth Hospital, Woodville, SA, Australia.
Psychiatry Res. 2014 Dec 30;220(3):954-9. doi: 10.1016/j.psychres.2014.08.051. Epub 2014 Sep 7.
Several international guidelines recommend routine depression screening in cardiac disease populations. No previous study has determined the prevalence and comorbidities of personality disorders in patients presenting for psychiatric treatment after these screening initiatives. In the first stage 404 heart failure (HF) patients were routinely screened and 73 underwent structured interview when either of the following criteria were met: (a) Patient Health Questionnaire ≥10; (b) Generalized Anxiety Disorder Questionnaire ≥7); (c) Response to one item panic-screener. Or (d) Suicidality. Patients with personality disorders were compared to the positive-screen patients on psychiatric comorbidities. The most common personality disorders were avoidant (8.2%), borderline (6.8%) and obsessive compulsive (4.1%), other personality disorders were prevalent in less than <3% of patients. Personality disorder patients had significantly greater risk of major depression (risk ratio (RR) 1.2; 95% confidence interval (CI) 1.2-13.3), generalized anxiety disorder (RR 3.2; 95% CI 1.0-10.0), social phobia (RR 3.8; 95% CI 1.3-11.5) and alcohol abuse/dependence (RR 3.2; 95% 1.0-9.5). The findings that HF patients with personality disorders presented with complex psychiatric comorbidity suggest that pathways facilitating the integration of psychiatric services into cardiology settings are warranted when routine depression screening is in place.
几项国际指南建议在心脏病患者群体中进行常规抑郁筛查。以前没有研究确定在这些筛查举措之后,因精神疾病就诊的患者中人格障碍的患病率和共病情况。在第一阶段,对 404 例心力衰竭 (HF) 患者进行了常规筛查,当满足以下标准之一时,对 73 例患者进行了结构化访谈:(a) 患者健康问卷 (PHQ) ≥10;(b) 广泛性焦虑症问卷 (GAD-7) ≥7;(c) 对惊恐筛查器的一个项目有反应;或 (d) 自杀意念。将人格障碍患者与阳性筛查患者的精神共病情况进行了比较。最常见的人格障碍是回避型(8.2%)、边缘型(6.8%)和强迫型(4.1%),其他人格障碍在不到 <3%的患者中较为常见。人格障碍患者发生重度抑郁症的风险显著更高(风险比 (RR) 1.2;95%置信区间 (CI) 1.2-13.3)、广泛性焦虑症(RR 3.2;95% CI 1.0-10.0)、社交恐惧症(RR 3.8;95% CI 1.3-11.5)和酒精滥用/依赖(RR 3.2;95% CI 1.0-9.5)的风险更高。这些发现表明,患有人格障碍的 HF 患者表现出复杂的精神共病情况,这表明当常规抑郁筛查到位时,有必要建立将精神科服务纳入心脏病学环境的途径。