Quirk Shae E, Berk Michael, Pasco Julie A, Brennan-Olsen Sharon L, Chanen Andrew M, Koivumaa-Honkanen Heli, Burke Lisa M, Jackson Henry J, Hulbert Carol, A Olsson Craig, Moran Paul, Stuart Amanda L, Williams Lana J
1 Deakin University, Geelong, VIC, Australia.
2 Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia.
Aust N Z J Psychiatry. 2017 Feb;51(2):141-150. doi: 10.1177/0004867416649032. Epub 2016 Jul 11.
We aimed to describe the prevalence and age distribution of personality disorders and their comorbidity with other psychiatric disorders in an age-stratified sample of Australian women aged ⩾25 years.
Individual personality disorders (paranoid, schizoid, schizotypal, histrionic, narcissistic, borderline, antisocial, avoidant, dependent, obsessive-compulsive), lifetime mood, anxiety, eating and substance misuse disorders were diagnosed utilising validated semi-structured clinical interviews (Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition and Structured Clinical Interview for DSM-IV Axis II Personality Disorders). The prevalence of personality disorders and Clusters were determined from the study population ( n = 768), and standardised to the Australian population using the 2011 Australian Bureau of Statistics census data. Prevalence by age and the association with mood, anxiety, eating and substance misuse disorders was also examined.
The overall prevalence of personality disorders in women was 21.8% (95% confidence interval [CI]: 18.7, 24.9). Cluster C personality disorders (17.5%, 95% CI: 16.0, 18.9) were more common than Cluster A (5.3%, 95% CI: 3.5, 7.0) and Cluster B personality disorders (3.2%, 95% CI: 1.8, 4.6). Of the individual personality disorders, obsessive-compulsive (10.3%, 95% CI: 8.0, 12.6), avoidant (9.3%, 95% CI: 7.1, 11.5), paranoid (3.9%, 95% CI: 3.1, 4.7) and borderline (2.7%, 95% CI: 1.4, 4.0) were among the most prevalent. The prevalence of other personality disorders was low (⩽1.7%). Being younger (25-34 years) was predictive of having any personality disorder (odds ratio: 2.36, 95% CI: 1.18, 4.74), as was being middle-aged (odds ratio: 2.41, 95% CI: 1.23, 4.72). Among the strongest predictors of having any personality disorder was having a lifetime history of psychiatric disorders (odds ratio: 4.29, 95% CI: 2.90, 6.33). Mood and anxiety disorders were the most common comorbid lifetime psychiatric disorders.
Approximately one in five women was identified with a personality disorder, emphasising that personality disorders are relatively common in the population. A more thorough understanding of the distribution of personality disorders and psychiatric comorbidity in the general population is crucial to assist allocation of health care resources to individuals living with these disorders.
我们旨在描述年龄分层的25岁及以上澳大利亚女性样本中人格障碍的患病率、年龄分布及其与其他精神障碍的共病情况。
使用经过验证的半结构化临床访谈(《精神疾病诊断与统计手册》第四版修订版轴I障碍的结构化临床访谈,研究版,非患者版和《精神疾病诊断与统计手册》第四版轴II人格障碍的结构化临床访谈)对个体人格障碍(偏执型、分裂样、分裂型、表演型、自恋型、边缘型、反社会型、回避型、依赖型、强迫型)、终生情绪、焦虑、饮食和物质滥用障碍进行诊断。从研究人群(n = 768)中确定人格障碍和人格障碍群组的患病率,并使用2011年澳大利亚统计局人口普查数据将其标准化为澳大利亚人口患病率。还研究了按年龄划分的患病率以及与情绪、焦虑、饮食和物质滥用障碍的关联。
女性人格障碍的总体患病率为21.8%(95%置信区间[CI]:18.7,24.9)。C类人格障碍(17.5%,95%CI:16.0,18.9)比A类(5.3%,95%CI:3.5,7.0)和B类人格障碍(3.2%,95%CI:1.8,4.6)更常见。在个体人格障碍中,强迫型(10.3%,95%CI:8.0,12.6)、回避型(9.3%,95%CI:7.1,11.5)、偏执型(3.9%,95%CI:3.1,4.7)和边缘型(2.7%,95%CI:1.4,4.0)最为常见。其他人格障碍的患病率较低(≤1.7%)。年龄较小(25 - 34岁)是患任何人格障碍的预测因素(优势比:2.36,95%CI:1.18,4.74),中年也是如此(优势比:2.41,95%CI:1.23,4.72)。患任何人格障碍的最强预测因素之一是有终生精神障碍病史(优势比:4.29,95%CI:2.90,6.33)。情绪和焦虑障碍是最常见的共病终生精神障碍。
约五分之一的女性被诊断患有人格障碍,这表明人格障碍在人群中相对常见。更全面地了解人格障碍在普通人群中的分布以及精神共病情况对于帮助将医疗保健资源分配给患有这些障碍的个体至关重要。